term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 Electron transport chain oxphos system in mitochondria 19 51 4.379047509578452 1.191991460669506e-05 17.57766990291262 50.45631067961165 1.00621396752225 0.3125021459260491 7.648293572467493 4.538458527560961 1.9412236823915887 0.3642771965747766 1.6426713321095097e-07 0.0009257347283437 0.0018751862862679 2.706366172303128e-07 9.480959994040974e-09 Nonalcoholic fatty liver disease 11 47 3.848240968402114 0.000118969001895 14.446601941747574 49.78883495145631 0.8140299356769594 0.4039994838731682 5.918094936421778 5.382150615191258 1.5259550974793896 0.3817978315095583 0.0006924962917422 0.022467997482696 0.0075508250565443 0.000983667285423 0.0031346425103821 Sphingolipid metabolism integrated pathway 7 9 2.807247883834996 0.0049966775435641 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 5.57302906638654e-08 0.0875404472016038 0.0007685743700876 7.191102350304072e-05 1.372168527141767e-06 Sphingolipid metabolism overview 7 9 2.807247883834996 0.0049966775435641 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 1.895974547524093e-08 0.0786913117950012 0.0005470061355849 3.982551880468722e-05 4.811826196161669e-07 Mitochondrial complex i assembly model oxphos system 9 27 2.6927386307506787 0.0070867800789076 8.808252427184467 26.563106796116504 0.7827212026364002 0.3851038550171766 4.050605834390814 3.9632288075289823 1.2210776523685654 0.3331428769936953 0.0015586270146485 0.2295798469686227 0.0965403494275516 0.0418926794657358 0.001050513287845 Mitochondrial complex iv assembly 7 12 2.6757730579786614 0.0074557111338791 4.645631067961165 11.985436893203884 1.036764412652062 0.2236438909453165 2.399566170297607 1.9080263664188637 1.5325215618909758 0.2795558816325345 0.0042060905423167 0.151306852499084 0.2827159209662828 0.0012777259352904 0.0010440793255692 Sphingolipid pathway 6 9 2.6297278973153806 0.0085453234554477 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 3.610828015877529e-06 0.1006582454154426 0.0190005699483642 0.0001534126882324 5.493155547881244e-05 Oxidative phosphorylation 9 30 2.507850214027105 0.0121468145276597 10.094660194174756 30.308252427184467 0.4493106572238387 0.4094278581483465 4.631390429635194 3.3340884045985604 1.35936739882113 0.3321380007425058 0.0012433440498619 0.2220822570468345 0.0905584027773802 0.0372180748890915 0.0007920809146458 Sphingolipid metabolism in senescence 6 14 2.4788388252498548 0.0131810852917055 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 5.049175209551961e-06 0.1049896535105009 0.0013656945298514 0.0001921663686867 7.568702219565374e-05 Cholesterol biosynthesis with skeletal dysplasias 2 5 2.4533270411748265 0.0141541588441653 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 0.0010300680130387 1.0 0.0660385900079411 0.011414919510753 0.0034377129995212 Mitochondrial complex iii assembly 2 11 2.43065914883403 0.0150713854291295 3.3106796116504853 9.259708737864075 1.0287385637679851 0.2644162586394033 1.7668969355473032 1.3138647920792297 1.192785152283574 0.2813694304742245 0.0110723766410014 0.0022827689145391 0.0090253131212995 0.005208827916976 0.0334620993119388 Statin inhibition of cholesterol production 3 5 2.3964061252133733 0.0165567339673557 2.0315533980582523 5.029126213592233 1.044092701346018 0.2144191485801186 1.2890406286437517 1.2084356467042294 1.2621579412510306 0.2395890160394713 0.0090696802174768 1.0 0.1277572387780678 0.0442367692127036 0.003721367796782 Oxidation by cytochrome p450 3 6 2.317562800987196 0.0204730938535366 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0005835015228144 0.0017062060788896 0.0002366501305723 0.0002054625318554 0.0027630263410089 Degradation pathway of sphingolipids including diseases 4 6 2.187466066852491 0.0287085177711041 3.645631067961165 6.432038834951456 0.0687547082162972 0.1728701573933007 1.3368036576958324 0.5554170290527195 1.9109030412897592 0.2451148181788838 0.0001138360199077 1.0 0.0841007109914387 0.0010713621736615 0.0005688349419973 Influence of laminopathies on wnt signaling 4 11 2.151208698407522 0.0314597307818194 2.929611650485437 10.199029126213592 1.172665957836072 0.274405530989148 1.5096443497648335 1.3031697834850824 0.8784257604250459 0.2713478851839423 0.0696598261722017 0.134742527043449 0.03403446937649 0.0356014336373073 0.0553856285019619 Glycosaminoglycan degradation 4 6 2.1475923431037094 0.0317461542277686 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 0.0004143495648334 1.0 0.1105474823156849 0.0331187861076589 0.0019884945269669 Acquired partial lipodystrophy barraquersimons syndrome 1 5 2.1350729467588003 0.0327550520425492 1.7402912621359223 4.497572815533981 0.9065154927122356 0.2548673055649036 1.4953091418597944 0.5048251951988992 1.235575791841686 0.2574096858611674 0.2035074389511066 1.0 0.0660385900079411 0.1583736196074974 0.0419919493306108 Cholesterol metabolism with bloch and kandutschrussell pathways 7 21 2.119590256234854 0.0340406149055441 7.092233009708738 23.070388349514563 1.3045876527781233 0.2885598195159411 3.1892169450204397 2.132138915277104 1.1515799969949023 0.3088028425519339 0.0001442205835487 1.0 0.0498890213657128 0.001886473535207 0.0003233683313873 Overlap between signal transduction pathways contributing to lmna laminopathies 6 16 1.9610868224886595 0.0498688956580062 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 0.1733442449929885 0.1952735388158895 0.0705821305211966 0.0958173315210673 0.020723717832043