Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Protein localization	0.6416065877518612	4.412072854482934	1.023856473003626e-05	0.0141106981355237	0.0013484219279976	77	Q9NS69,O60830,Q99595,Q9NX63,P62072,Q9Y5Y5,Q8N4H5,Q13505,O60220,P09601,Q96B49,O14925,P21796,Q13011,Q9BY49,Q9Y584,P40855,O43615,P56589,Q9NR77,Q8N4Q1,O75381,Q15067,P12236,P39210,P51648,Q5JRX3,P12235,Q10713,O14734,O43681,P49069,P50402,Q9Y5J9,P46379	35
Sphingolipid metabolism	0.828762488873076	4.115804033710154	3.8583202594644206e-05	0.0521457358652577	0.0019126244714774	27	P27544,O95470,O15269,P06280,P51648,P04062,O15121,Q9NZJ7,Q13510,Q96G23,P16278,Q06136,P10619,P17900,P07602,P06865	16
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins	0.6229928020865905	4.082259645082126	4.4599928424648994e-05	0.060028836359729	0.0021346448501177	63	Q9Y6M9,P00403,O43676,P00846,Q9UDW1,P03915,P24539,O14949,Q86Y39,P21912,P56385,P13073,O75964,P20674,Q9P0J0,Q16134,O96000,O95168,Q8N8Q8,Q9NPL8,O75880	21
Zinc efflux and compartmentalization by the slc30 family	0.9592435604825562	3.94091121314348	8.117266942964108e-05	0.1065565512212623	0.0030544001538166	2	Q8TAD4	1
Respiratory electron transport	0.6108046884633239	3.918006431852348	8.928432448906953e-05	0.1165602419124904	0.0030544001538166	53	O14949,O95168,Q8N8Q8,Q9Y6M9,Q86Y39,P20674,Q9P0J0,Q16134,P00403,O43676,P21912,O96000,Q9UDW1,P03915,Q9NPL8,P13073,O75880	17
Mitochondrial protein import	0.7200946302391127	3.8074146029006126	0.0001404272074971	0.1771049854904747	0.0033605683449326	36	Q10713,Q96B49,Q9NS69,O60830,Q9NX63,Q99595,O14925,P62072,P21796,Q8N4Q1,Q9Y584,Q8N4H5,O43615,P12235,Q9Y5J9,Q13505,O60220,Q5JRX3	18
Proton coupled monocarboxylate transport	0.9188131724812516	3.7535519376724538	0.0001743463876693	0.2149547219522089	0.0035111375169609	2	P53985	1
Transport of small molecules	0.4669945518957344	3.7532666393136287	0.0001745450206558	0.2151711688842949	0.0035111375169609	162	P35670,P05023,Q15904,P30519,Q9H4I9,O94905,Q9H2J7,Q9UL46,P49721,Q8TDW0,Q15043,P09601,Q8IYU8,Q99623,Q9UBX3,P45880,P08183,Q93050,O75477,P35610,P38571,O15439,P28072,Q9C0H2,P21796,P07237,P40855,P56589,P30825,Q70HW3,Q8WWC4,Q9BUN8,P12236,O15118,P20618,P51790,O00400,P16615,P28070,Q9BPX6,Q15758,Q9Y6M7,P12235,Q9GZP9,P20020,P49720,P53985,Q10713,P02786,Q8WTV0,Q96PU5,Q8TAD4,Q9Y277,Q96QD8,Q8TB61,P35613,Q9HD20,Q8NEW0	58
Vitamin d calciferol metabolism	0.86338441473754	3.489250362453588	0.0004843772491627	0.4895581223512806	0.0070770065456617	2	P04062	1
Intrinsic pathway of fibrin clot formation	0.8154548418650329	3.2532849839052163	0.0011407902365987	0.79491294041964	0.0128733077105614	2	P42785	1
Notch4 activation and transmission of signal to the nucleus	0.8092598630583586	3.2222573889286887	0.0012718482554756	0.8290610740346398	0.0140836094924267	2	Q92542	1
The citric acid tca cycle and respiratory electron transport	0.4844085363788377	3.107413373953405	0.0018873228891698	0.9273483592102262	0.018318910280893	96	Q9Y6M9,P00403,O43676,P00846,Q9UDW1,P03915,P24539,O14949,Q86Y39,P21796,P21912,P56385,P13073,O75964,P20674,Q9P0J0,Q16134,Q9H9P8,O96000,O95168,P53985,Q8N8Q8,Q9NPL8,P35613,O75880	25
Glycosphingolipid metabolism	0.802650591805058	3.066418946137084	0.0021663953570205	0.9507190950223144	0.019913620897646	16	P06280,P04062,Q9NZJ7,Q13510,P16278,P06865,P10619,P17900,P07602	9
Notch3 activation and transmission of signal to the nucleus	0.7691555265731995	3.0183377894366226	0.0025416542798464	0.9707626125329628	0.021776642842141	2	Q92542	1
Noncanonical activation of notch3	0.7691555265731995	3.0183377894366226	0.0025416542798464	0.9707626125329628	0.021776642842141	2	Q92542	1
Sphingolipid de novo biosynthesis	0.8800862988508698	3.0091916764289968	0.0026194379992214	0.9737620941317356	0.0222367538642481	11	P27544,O95470,P51648,O15121,Q96G23,O15269	6
Hs gag degradation	0.8303979125896814	3.003776780864172	0.0026665088360211	0.97542578559973	0.0222958690626347	3	P54802,P16278	2
Clec7a dectin 1 induces nfat activation	0.7636126507988263	2.9897274964271774	0.0027922643093147	0.979371545967148	0.0230694217936245	2	O43865	1
Metal ion slc transporters	0.8261578604044242	2.983441468010397	0.0028502654681188	0.9809714970985448	0.0231354881271868	3	Q8TAD4,Q8NEW0	2
Zinc transporters	0.8261578604044242	2.983441468010397	0.0028502654681188	0.9809714970985448	0.0231354881271868	3	Q8TAD4,Q8NEW0	2
Heme degradation	0.8886758170464049	2.9732938350783815	0.0029462225695586	0.983350795854599	0.0233677538659853	4	P30519	1
P38mapk events	0.7577437235083152	2.959318845066854	0.0030831991604545	0.9862414010451304	0.0236408923022075	2	P11234	1
Acyl chain remodelling of pg	0.75285295076624	2.933886999064799	0.0033474605498151	0.99047722758937	0.0236408923022075	2	Q8NF37	1
Formation of fibrin clot clotting cascade	0.8157208088714797	2.9331582094106716	0.003355328649192	0.9905810051348436	0.0236408923022075	3	P42785,Q9UNN8	2
Keratan sulfate degradation	0.8758020993152303	2.915365167139193	0.0035527258252248	0.9928451427634952	0.0236408923022075	4	P16278,P06865	2
Abc transporters in lipid homeostasis	0.8111069699858962	2.9108260913411317	0.003604745952308	0.9933452678936022	0.0238256541990648	3	P40855	1
Reduction of cytosolic ca levels	0.783105022831041	2.773903063383921	0.0055388179640791	0.9995513417795752	0.0331374109230254	3	P20020,P16615	2
Cytochrome p450 arranged by substrate type	0.7820451374959319	2.768673119948612	0.0056285074150319	0.999604134926078	0.0335294776483448	3	Q16850	1
Molecules associated with elastic fibres	0.7199217476361447	2.7604453870853343	0.0057722608010846	0.9996761113402808	0.0338127202258713	2	P55081	1
Elastic fibre formation	0.7199217476361447	2.7604453870853343	0.0057722608010846	0.9996761113402808	0.0338127202258713	2	P55081	1
Laminin interactions	0.7199217476361286	2.7604453870852463	0.0057722608010861	0.9996761113402816	0.0338127202258713	2	P07942	1
Formyl peptide receptors bind formyl peptides and many other ligands	0.7186175415715883	2.7534962835762817	0.0058962439640857	0.9997275919072488	0.034386498412399	2	P04083	1
Mitochondrial calcium ion transport	0.7277995371343872	2.734707547823451	0.00624357205504	0.999832285057606	0.0359848481308339	17	Q10713,P21796,Q9H4I9,Q9BPX6,Q9Y277,Q8WWC4,Q8IYU8,P45880	8
Ptk6 regulates proteins involved in rna processing	0.7746249184605254	2.7319604859951996	0.0062958691305268	0.9998440992719588	0.0361101915420298	3	O75525,P23246	2
Mucopolysaccharidoses	0.8306688417618159	2.708832268817847	0.0067520465192403	0.999917575123451	0.037942674367229	4	P54802,P16278,P15586	3
Metabolism of lipids	0.396129541639418	2.697018212271648	0.0069963443806908	0.9999414164005802	0.0387288309571021	170	Q9P035,Q96N66,P50897,O15121,Q14739,Q9UG56,Q9UKU0,Q06136,P10619,Q14534,P07602,O95470,P35610,Q9UMR5,O95772,Q13510,P06865,Q16880,Q9NPH0,Q15067,Q15800,Q15392,Q9NUQ2,P51648,Q9BWD1,Q9NZJ7,Q96G23,P16278,Q16850,O15269,P27544,Q10713,Q8NF37,P06280,P04062,P23786,Q9H7Z7,Q8NCC3,P30536,P17900,Q8IV08	41
Creb phosphorylation	0.7055754809259871	2.6836633650857906	0.0072820388372472	0.9999607064840684	0.0401090075638854	2	Q15418	1
Slc mediated transmembrane transport	0.6116217867416021	2.6774511821169926	0.0074184662341925	0.9999675306642056	0.0405387052482646	26	P53985,P12235,Q8NEW0,O00400,Q9H2J7,Q8TAD4,P30825,Q70HW3,Q15043,Q9Y6M7,Q96QD8,P35613,Q8TB61,Q9UBX3,P12236	15
Synthesis secretion and deacylation of ghrelin	0.7628879862237377	2.6735377216494323	0.0075055834559036	0.9999712548705012	0.0406654154099408	3	P67812	1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip	0.7628879862237377	2.6735377216494323	0.0075055834559036	0.9999712548705012	0.0406654154099408	3	P67812	1
Mitophagy	0.8052228356575778	2.6482629800196507	0.0080906560677691	0.9999873202648616	0.0433133603221109	11	Q96B49,Q9NS69,Q8N4H5	3
Alpha oxidation of phytanate	0.8123980424143427	2.623661054422121	0.0086990306398404	0.999994589008714	0.0454538116420526	4	O43808,Q9BY49,P51648	3
Glycosaminoglycan metabolism	0.7670904061789308	2.597779764951784	0.0093828651886873	0.9999979236525884	0.0467014174668742	12	P15586,Q7LGA3,P54802,P16278,P06865,Q8TB61,O43505	7
Interleukin receptor shc signaling	0.6882947505705944	2.590166458031477	0.0095929533244696	0.9999984531590316	0.0473844100155297	2	O00459	1
Linoleic acid la metabolism	0.6873165960221697	2.5848408257409	0.0097423962502898	0.9999987454673988	0.0479519361539088	2	O95864	1
O linked glycosylation of mucins	0.8003262642740574	2.56688167286138	0.0102617623137803	0.9999993943180012	0.0498018394808643	4	Q10471,O43505,Q10472	3
Keratan sulfate keratin metabolism	0.8511033932891605	2.536641048648518	0.0111921646279609	0.999999835821608	0.0537533719848088	5	P16278,P15586,P06865	3
Pink1 prkn mediated mitophagy	0.8548585848277619	2.509856197127853	0.0120780335736336	0.9999999526819116	0.0576093147773318	8	Q96B49,Q9NS69,Q8N4H5	3
Platelet calcium homeostasis	0.7833605220228315	2.486395032636277	0.0129044632240349	0.9999999851900616	0.0611310408019129	4	P20020,Q13586,P16615	3
Cristae formation	0.6547487038072399	2.465761321655404	0.0136722404092863	0.9999999949707448	0.0635605300650694	19	O75964,Q9NX63,Q5XKP0,P56385,P00846,Q16891,Q13505,P24539	8
Class b 2 secretin family receptors	0.719356637617171	2.45300522594098	0.014166828048618	0.9999999974929826	0.0655451911049393	3	Q9Y3E5	1
Endosomal vacuolar pathway	0.7718158543709532	2.431161804917284	0.0150504916381839	0.9999999992779168	0.0689441663161693	4	Q9UIQ6,P10321	2
Selective autophagy	0.568039927718816	2.4171766550247	0.0156414239525879	0.9999999996860784	0.0714154488361581	28	Q96B49,Q9NS69,Q8N4H5	3
Ticam1 rip1 mediated ikk complex recruitment	0.6547114444082133	2.405243255265745	0.0161617038531394	0.9999999998492948	0.0728326134680438	2	Q13546	1
Ikk complex recruitment mediated by rip1	0.6547114444082133	2.405243255265745	0.0161617038531394	0.9999999998492948	0.0728326134680438	2	Q13546	1
Complex i biogenesis	0.557624795287582	2.3668884267927703	0.0179383397185337	0.999999999987737	0.0766105093209995	29	O95168,Q9Y6M9,Q86Y39,Q9P0J0,O43676,O96000,P03915,Q9NPL8	8
Heparan sulfate heparin hs gag metabolism	0.8094593871261535	2.349364802673134	0.0188054720822823	0.9999999999964015	0.0794590160243756	5	P16278,Q7LGA3	2
Class i peroxisomal membrane protein import	0.7436641102005103	2.339060922438944	0.0193322807303384	0.9999999999982924	0.0798693029629925	11	P51648,O43808,Q9Y5Y5,P40855,P56589,Q5T8D3,Q9NR77,O75381	8
Processing of smdt1	0.7171718615501248	2.335698055117287	0.0195069839369268	0.9999999999986664	0.0798693029629925	12	Q10713,Q9H4I9,Q9BPX6,Q8WWC4,Q8IYU8	5
Signalling to ras	0.688519243313749	2.29303042237162	0.021846253531764	0.9999999999999516	0.0873850141270562	3	P11233,P11234	2
Attachment of gpi anchor to upar	0.7429730559881736	2.2915062765465755	0.0219341492756519	0.9999999999999571	0.087484480444267	4	O43292,Q9H490	2
Ecm proteoglycans	0.6862361382909198	2.281060802029971	0.0225448492243309	0.999999999999982	0.0891744010589012	3	P07942,P05556	2
Peptide ligand binding receptors	0.8387480742271374	2.236294721155062	0.0253324720126326	0.9999999999999996	0.0979428165836605	6	P07602,Q9NZJ7,P42892	3
Class a 1 rhodopsin like receptors	0.8387480742271374	2.236294721155062	0.0253324720126326	0.9999999999999996	0.0979428165836605	6	P07602,Q9NZJ7,P42892	3
Pregnenolone biosynthesis	0.7303305097258985	2.2295371913676143	0.0257781836025907	0.9999999999999998	0.0993892190010999	4	O95772	1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	0.6706259076717792	2.1991643637431664	0.0278662372627143	1.0	0.1012191400611547	14	Q5JRA6,Q15293,O43852,P07942,P07237,Q07065,Q02818,Q9BTY2	8
Glycerophospholipid biosynthesis	0.5450010836029414	2.197461486074625	0.0279875041864985	1.0	0.1012191400611547	26	Q9NUQ2,Q96N66,Q8NF37,Q9UG56,Q9NPH0,Q8IV08	6
Ire1alpha activates chaperones	0.5813279646350554	2.191905131085998	0.0283863575100558	1.0	0.1023383486336557	22	Q9NWM8,Q9Y5M8,P43307,O14773	4
Transport of bile salts and organic acids metal ions and amine compounds	0.8269670257917155	2.185002077410764	0.0288886942725492	1.0	0.1037931242717703	6	P53985,Q9H2J7,Q8TAD4,P35613,Q8NEW0	5
Nicotinamide salvaging	0.6586588882645433	2.1351054347248444	0.0327523988186495	1.0	0.1092796383660711	3	Q9BQG2	1
Amino acid transport across the plasma membrane	0.7509791122715501	2.079011518575711	0.03761629176914	1.0	0.121421890640852	5	Q15758,P30825,Q9H2J7,Q96QD8	4
Role of phospholipids in phagocytosis	0.7394310322215575	2.0246023897394885	0.0429082086807486	1.0	0.1362851113246661	5	O00459,Q8IV08	2
Gpcr ligand binding	0.727312354487622	2.019015088242258	0.0434856513059815	1.0	0.1373114889444228	9	P07602,Q9NZJ7,P42892	3
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol	0.688043166021846	2.0189038099627967	0.0434972181659085	1.0	0.1373114889444228	4	O14734	1
Cholesterol biosynthesis	0.6286392241589973	2.0186064730618405	0.0435281377057248	1.0	0.1373114889444228	15	Q15392,Q15800,Q9BWD1,Q14739,Q16850,Q14534	6
Transport of inorganic cations anions and amino acids oligopeptides	0.6818742870205893	2.0169433976001687	0.0437014205177754	1.0	0.1375455140105949	11	Q9H2J7,P30825,Q70HW3,Q15758,Q9Y6M7,Q96QD8,Q9UBX3	7
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.6810418774034892	2.01252307030059	0.0441648272584118	1.0	0.1386895480422526	11	P09601,P51648,O43681,P49069,P50402,P46379	6
Role of lat2 ntal lab on calcium mobilization	0.631356113668232	1.9880998209456435	0.0468006511825613	1.0	0.1451227676054369	3	O00459	1
Adp signalling through p2y purinoceptor 1	0.6311154598825703	1.986793066212568	0.0469453333248135	1.0	0.1451227676054369	3	Q9UBI6,P29992	2
Adrenaline noradrenaline inhibits insulin secretion	0.6311154598825705	1.986793066212568	0.0469453333248135	1.0	0.1451227676054369	3	Q9UBI6,P04899	2
G protein activation	0.6311154598825703	1.986793066212568	0.0469453333248135	1.0	0.1451227676054369	3	Q9UBI6,P29992	2
Synthesis of pa	0.7148688204713178	1.9575869477603145	0.0502785001484056	1.0	0.1537148859162709	9	Q9NUQ2,Q9NPH0	2
Formation of atp by chemiosmotic coupling	0.6917913251780201	1.950905169103044	0.0510683276429206	1.0	0.1554448218604691	10	O75964,P00846	2
Incretin synthesis secretion and inactivation	0.6713328928428495	1.9342529328173228	0.0530820371101765	1.0	0.1581070118217276	4	P67812	1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1	0.6713328928428495	1.9342529328173228	0.0530820371101765	1.0	0.1581070118217276	4	P67812	1
Metabolism of porphyrins	0.6858702074770605	1.9204002751220657	0.0548073588317654	1.0	0.1615129810159033	10	P09601,P22830,P30519	3
Organelle biogenesis and maintenance	0.3957964358031934	1.918907148336287	0.0549960858125118	1.0	0.1617257777706915	89	P53350,Q9NX63,P00846,O95684,Q13505,A6NIH7,P41208,P24539,P56385,O75964,Q5XKP0,O75935,O43805,Q16891,Q6UXV4,Q10713,O94927,P30153,A0AVF1,O43924,Q9UPT5,Q9H6D7	22
Runx3 regulates p14 arf	0.5673296380828199	1.9036204417831484	0.0569596345741441	1.0	0.1653974326127866	2	P25440	1
Mitochondrial biogenesis	0.4939606790219402	1.900436350316523	0.0573758804015458	1.0	0.1662582922700326	30	O75964,Q9NX63,Q5XKP0,P56385,P00846,Q16891,Q13505,P24539	8
O linked glycosylation	0.757983024217394	1.8784611257779793	0.0603181102681655	1.0	0.1733365156360534	6	Q10472,Q10471,O43505,Q8NAT1	4
Antigen activates b cell receptor bcr leading to generation of second messengers	0.6599677186961914	1.8762276090783716	0.0606240324778029	1.0	0.173818918005482	4	Q13586,O43865	2
Cytoprotection by hmox1	0.4016195355059572	1.8577618608353623	0.0632028394070787	1.0	0.1787702883442134	65	Q8N8Q8,P28072,P20674,P30519,P49720,P00403,P28070,Q8TCT9,P49721,P09601,P13073,O75880	12
Ras processing	0.7533512059825174	1.8575049646837	0.0632393455165769	1.0	0.1787702883442134	6	P49354,O60725,O43924	3
Synaptic adhesion like molecules	0.7108291217503168	1.8379608579416655	0.0660681732796737	1.0	0.1843464426987258	8	P41440,O95197	2
Sialic acid metabolism	0.6844557973712684	1.7610507042264405	0.0782298214647356	1.0	0.209935452328147	5	P10619	1
Regulation of pten localization	0.5396152592109493	1.7383979617304886	0.0821407156075166	1.0	0.2159305175440021	2	P98170	1
Rhoa gtpase cycle	0.4230903806895454	1.731347466673312	0.0833898102189898	1.0	0.2171577046603337	44	O00459,P02786,Q96HY6,O15498,P30519,P49257,Q96CS3,Q14739,P41440,Q5T8D3,Q07021,O15173,P42167,Q15904,P51572	15
Metabolism of fat soluble vitamins	0.6726288242389038	1.7034045799355306	0.0884923812102485	1.0	0.2287289108376627	5	Q8N0U8	1
Pp2a mediated dephosphorylation of key metabolic factors	0.5786226367217846	1.6972860901205515	0.0896425857323819	1.0	0.2308421317190095	3	P30154	1
Phospholipid metabolism	0.4374050626855487	1.6882803141173148	0.0913574323081902	1.0	0.2339559336600887	39	Q10713,Q9NUQ2,Q96N66,Q8NF37,Q9UG56,Q9NPH0,Q8IV08	7
Rhod gtpase cycle	0.4772139725971211	1.6821313189363614	0.0925433784729006	1.0	0.236556554917838	26	P49257,Q14739,P50402,Q9Y6M7,O15173,P42167	6
Transport of vitamins nucleosides and related molecules	0.6582393880428902	1.672961046749445	0.0943349646758253	1.0	0.2402512494863222	9	P12235,O00400,Q8TB61	3
Activation of smo	0.5268992500815072	1.6616598267170122	0.0965810003966478	1.0	0.2446248696177869	2	P48729	1
Diseases of carbohydrate metabolism	0.6732370350186019	1.6541989073444157	0.0980871048079765	1.0	0.2478766520067652	8	P10253,P16278,P54802,P15586	4
Signaling by fgfr4 in disease	0.5252689925008097	1.6517810786960063	0.0985791872534076	1.0	0.2478766520067652	2	P62993	1
Signaling by ntrk3 trkc	0.5252689925008097	1.6517810786960063	0.0985791872534076	1.0	0.2478766520067652	2	P62993	1
Erythropoietin activates phospholipase c gamma plcg	0.5252689925008069	1.65178107869599	0.0985791872534109	1.0	0.2478766520067652	2	P07948	1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.6587887245058035	1.6355436441099689	0.1019351333095106	1.0	0.2526535089885728	5	P12235,P05141,P12236	3
Hyaluronan uptake and degradation	0.6128079085835814	1.631691895604952	0.1027444082011435	1.0	0.2532134063000628	4	P06865	1
Hyaluronan metabolism	0.6128079085835814	1.631691895604952	0.1027444082011435	1.0	0.2532134063000628	4	P06865	1
Ion channel transport	0.4617655098766064	1.6185721738942769	0.1055393462008955	1.0	0.2579024868430335	29	P35670,P05023,Q93050,Q9C0H2,P51790,P16615,Q96PU5,Q9NW15,Q9HD20,P20020,Q15904	11
Constitutive signaling by egfrviii	0.6031532625049457	1.5809240167403396	0.1138954121945539	1.0	0.2716268593230942	4	Q16543,P07900	2
Constitutive signaling by ligand responsive egfr cancer variants	0.6031532625049457	1.5809240167403396	0.1138954121945539	1.0	0.2716268593230942	4	Q16543,P07900	2
Signaling by egfr in cancer	0.6031532625049457	1.5809240167403396	0.1138954121945539	1.0	0.2716268593230942	4	Q16543,P07900	2
Runx1 regulates transcription of genes involved in differentiation of myeloid cells	0.5083143136615516	1.548520325071895	0.1214970720707815	1.0	0.2839022492159003	2	Q13951	1
Tp53 regulates transcription of death receptors and ligands	0.5073361591131402	1.5425349107444064	0.1229436612215981	1.0	0.2858388639456943	2	P04637	1
Caspase activation via death receptors in the presence of ligand	0.5073361591131396	1.5425349107444029	0.122943661221599	1.0	0.2858388639456943	2	Q13546	1
Regulation by c flip	0.5073361591131396	1.5425349107444029	0.122943661221599	1.0	0.2858388639456943	2	Q13546	1
Glutamate neurotransmitter release cycle	0.5491962937780481	1.5313330531911826	0.1256871005271842	1.0	0.289795644794873	3	Q96QD8	1
Egr2 and sox10 mediated initiation of schwann cell myelination	0.6641699009034504	1.523780508872352	0.1275635500868692	1.0	0.2916939168378493	7	Q9NR77,Q16850	2
Tp53 regulates transcription of genes involved in g1 cell cycle arrest	0.5008151287903484	1.5025577773904355	0.1329531182783578	1.0	0.3000632978379849	2	P04637	1
Small interfering rna sirna biogenesis	0.5388911205084487	1.472663675370803	0.1408417458776827	1.0	0.3122816985275138	3	O75569	1
Bile acid and bile salt metabolism	0.6482041868586688	1.4465481662501785	0.1480235125332827	1.0	0.3220323438811855	7	Q9H4L5,O14734,O14975	3
Synthesis of bile acids and bile salts	0.6482041868586688	1.4465481662501785	0.1480235125332827	1.0	0.3220323438811855	7	Q9H4L5,O14734,O14975	3
Peroxisomal lipid metabolism	0.5566758913733066	1.4376152581653263	0.1505432492026754	1.0	0.3259813258866046	12	O14975,P51648,O14734,O43808,Q9BY49,Q15067	6
Synthesis of very long chain fatty acyl coas	0.6285583162908124	1.4318233807661578	0.1521943741659428	1.0	0.3287359758270875	8	Q9UKU0,Q9P035	2
Metabolism of steroid hormones	0.6600824011444437	1.4263688386209563	0.15376190360903	1.0	0.3296414877321432	6	O95772	1
Cellular response to chemical stress	0.3623419370374026	1.4074454534538148	0.1592953410364785	1.0	0.3380763507012725	75	Q8N8Q8,P20618,P28072,P20674,P30519,P49720,P07237,P00403,P28070,Q8TCT9,P49721,P09601,P13073,O75880	14
Striated muscle contraction	0.6115148794712258	1.4007693767067209	0.1612830488785368	1.0	0.3407641929468645	5	P08670,Q9NYL9	2
G alpha s signalling events	0.654636489044502	1.4007183112546846	0.1612983247594308	1.0	0.3407641929468645	6	O60658,Q9Y3E5	2
Abc family proteins mediated transport	0.3578296084344193	1.3863061873422282	0.1656534283429094	1.0	0.3487901315488473	54	P08183,O75477,O15439,P28072,O94905,P49720,P40855,P28070,P56589,P49721,Q9BUN8	11
Autophagy	0.3967695613264022	1.3741202124721943	0.1694043654269772	1.0	0.352714742327823	41	Q96B49,Q9NS69,Q8N4H5	3
Gamma carboxylation hypusine formation and arylsulfatase activation	0.5975825348052166	1.359815770209273	0.1738882306380214	1.0	0.3575657246304795	9	P38435,P49366,O60725,Q9BU89,Q9HA64	5
Unfolded protein response upr	0.4042137947086757	1.351182313217689	0.1766370388085885	1.0	0.3621450662722612	38	Q9NWM8,Q9Y5M8,P43307,O14773	4
Rhog gtpase cycle	0.4090161499243913	1.3376046636016117	0.1810253433953395	1.0	0.368421080106644	36	P02786,O15498,P49257,Q14739,P50402,Q86XL3,O15173,P42167	8
Phase i functionalization of compounds	0.5143038222592251	1.321934581866852	0.1861899356490497	1.0	0.3761741349066681	15	O43169,Q16850	2
Collagen biosynthesis and modifying enzymes	0.5541275275489173	1.315518404079845	0.1883357362290578	1.0	0.3783068044658933	11	P13674,P07237,Q32P28,O15460	4
Integrin cell surface interactions	0.5933846070289353	1.309690227489926	0.1903006508878824	1.0	0.3817013055381225	5	P35613	1
Rac2 gtpase cycle	0.4046767751004199	1.2985802110234257	0.1940880328381831	1.0	0.3870606172117789	36	O00459,P02786,P49257,Q14739,P50402,Q86XL3,Q13505,O15173,P42167	9
Nicotinate metabolism	0.5907384028750514	1.296358221900804	0.1948520984608284	1.0	0.3873881070956251	5	Q9BQG2	1
Ion transport by p type atpases	0.5852215142462803	1.2951650360050295	0.1952633034388564	1.0	0.3873881070956251	9	P35670,P05023,P16615,P20020,Q9HD20	5
Signaling by mras complex mutants	0.467231822627972	1.2948596738328897	0.1953686419070155	1.0	0.3873881070956251	2	P31946	1
Caspase activation via extrinsic apoptotic signalling pathway	0.5075016307892957	1.2924802551590362	0.1961908794210898	1.0	0.3884635387110879	3	Q9UKG1,Q13546	2
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components	0.4646234104988552	1.2786209054867563	0.2010305845485134	1.0	0.3957878742600519	2	P12814	1
Signaling by flt3 fusion proteins	0.5445322878843462	1.2684127080805183	0.2046506057536099	1.0	0.4017751637708778	4	Q14789	1
G1 s specific transcription	0.5951671553461377	1.2633443135051678	0.2064654673435089	1.0	0.4047656337186305	8	Q9Y619,P00374	2
Rac3 gtpase cycle	0.4081307562259504	1.2556356883449495	0.2092480859258629	1.0	0.4090652722043631	33	O00459,O15498,P49257,Q14739,Q9UQB8,P50402,Q15758,O15173,P42167	9
Platelet homeostasis	0.557485611346987	1.2371683351638454	0.2160245944709662	1.0	0.420535956698038	10	Q13586,P16615,P30153,P30154,P20020,P30626	6
Sulfur amino acid metabolism	0.5509567730407541	1.201563845010444	0.2295325564322561	1.0	0.4421890954617671	10	Q9UBX3	1
Fceri mediated ca 2 mobilization	0.5698284634278468	1.1907354453796335	0.2337574583394297	1.0	0.4469875489311388	5	Q08209,O43865	2
Aryl hydrocarbon receptor signalling	0.4898891063274391	1.1906297609553649	0.2337989629135495	1.0	0.4469875489311388	3	O00170,P08238	2
Regulation of hmox1 expression and activity	0.3578747900217854	1.1843879605079763	0.2362595238331464	1.0	0.4504508503851747	47	Q8TCT9,P09601,P49720,P28072	4
Notch hlh transcription pathway	0.4437561134659117	1.148339234815617	0.2508285481474943	1.0	0.4668140412550432	2	Q92769	1
Response to elevated platelet cytosolic ca2	0.3905484063688886	1.1465632834221586	0.2515621585108618	1.0	0.4674274109947473	35	Q8NBX0,Q92520,O15439,O94919,O43852,Q9NZJ7,Q9NUQ9,Q08380,Q6UXV4,P07602,P13473,Q96JJ7	12
Transcriptional regulation by e2f6	0.5719494606505123	1.1454204337266622	0.2520350377982674	1.0	0.4676799899251272	8	Q9UBK9,Q99496,P45973,P31350,Q15022	5
Cargo concentration in the er	0.4928478820043289	1.1418353453045489	0.2535224674667293	1.0	0.4684937836916217	14	Q5JRA6,P49755,Q96PC5,P49257,Q12907,Q13190	6
Diseases associated with n glycosylation of proteins	0.5580887053396342	1.1312748024516075	0.2579394464241362	1.0	0.4710788837325015	5	Q9BT22,Q2TAA5	2
Cilium assembly	0.3376214871049465	1.1281727397687982	0.2592469741610026	1.0	0.4728446782332084	59	P53350,Q10713,O94927,O75935,P30153,A0AVF1,O43805,O43924,O95684,Q9UPT5,A6NIH7,P41208,Q9H6D7	13
Cardiac conduction	0.4963729603062313	1.1213768547448677	0.2621274838986509	1.0	0.4763758425372735	13	P05023,Q13586,P16615,O43865,Q9HD47,P20020	6
Muscle contraction	0.4043670760573942	1.1157907099465514	0.2645117313100669	1.0	0.4799245530174809	27	P05023,P60660,P04083,Q13586,P16615,O43865,Q9HD47,P20020,P08670	9
Mastl facilitates mitotic progression	0.55472117890577	1.114205819475081	0.2651908994246916	1.0	0.4805286793752898	5	P30154	1
Prevention of phagosomal lysosomal fusion	0.5145187601957439	1.106446780513457	0.2685331869705383	1.0	0.4859505391331253	4	P20339,P51149,O14964	3
Disorders of transmembrane transporters	0.337628165455745	1.1024165289733825	0.270280628870396	1.0	0.4884759282188928	77	P53985,O75477,P28072,O94905,O00400,Q9BUN8,P28070,Q9BTX1,Q8NFH4,P49721,P35613,P49720	12
Phosphorylation of emi1	0.4735347681038676	1.0957818106309114	0.27317427039767	1.0	0.4924232302752806	3	P53350	1
Transport of connexons to the plasma membrane	0.5096247960848213	1.0799860153214451	0.2801484076997846	1.0	0.4995843907712857	4	Q9BVA1,Q13509,P68371	3
Gap junction assembly	0.5096247960848213	1.0799860153214451	0.2801484076997846	1.0	0.4995843907712857	4	Q9BVA1,Q13509,P68371	3
Vitamin b5 pantothenate metabolism	0.5076672104404478	1.0694008418995065	0.2848890881308255	1.0	0.506307367894476	4	Q9NRN7,Q9Y289,Q9NVE7	3
Protein protein interactions at synapses	0.465206948843637	1.0580394135576026	0.2900374739853544	1.0	0.5121294889049316	16	P41440,P10586,O95197	3
Diseases of glycosylation	0.457646385722661	1.0572907882301268	0.2903788960865858	1.0	0.5121294889049316	17	Q9BT22,P16278,P06865,P10619,O43505	5
Cell surface interactions at the vascular wall	0.4482807949103276	1.0461452065888934	0.2954939962297307	1.0	0.5165562553738869	18	P53985,P35613,Q08722,Q9UNN8	4
The phototransduction cascade	0.540049804837155	1.0398160628245152	0.2984253649455031	1.0	0.5210244107476205	5	P49356,P49354	2
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1	0.4235409194652738	1.0218186406893368	0.3068667450815341	1.0	0.5330801529075961	2	P61088	1
Activated tak1 mediates p38 mapk activation	0.4235409194652738	1.0218186406893368	0.3068667450815341	1.0	0.5330801529075961	2	P61088	1
Signaling by ptk6	0.4837152398220203	1.007561293542598	0.3136651186086383	1.0	0.5421758214555292	12	P23246,P46108,P18031,Q07666,O75525	5
Stimuli sensing channels	0.4996377363124375	1.0063485241282268	0.3142479461612906	1.0	0.542283067541225	11	Q9C0H2,P51790,Q9NW15,Q96PU5	4
Synthesis of substrates in n glycan biosythesis	0.4679325244698179	0.9880000918015214	0.3231526032378062	1.0	0.5503506911583743	14	P10619	1
Dissolution of fibrin clot	0.4153896315617889	0.9708375499102836	0.3316291805197178	1.0	0.5599772537242924	2	P07355	1
Initiation of nuclear envelope ne reformation	0.4494464821706311	0.9562808248785424	0.3389303749115062	1.0	0.5695343345970589	16	Q14739,P50402,P30153,Q86XL3	4
Peptide hormone metabolism	0.453960833783956	0.9418116088034354	0.3462891006430673	1.0	0.5790955080633462	15	Q9UPT5,P67812,Q8TAD4,Q8NEW0	4
Iron uptake and transport	0.4307216453387509	0.9272521829318308	0.353795614865855	1.0	0.5886961575124334	18	P30519,P09601	2
Peroxisomal protein import	0.4103745125947883	0.9265681723000928	0.3541507863997708	1.0	0.5886961575124334	21	P39210,Q13011,O14734,Q9BY49,O75381,Q15067	6
Displacement of dna glycosylase by apex1	0.4429267348765794	0.9183104695312068	0.3584563476755336	1.0	0.5944294033137881	3	P78549	1
Biological oxidations	0.343643832403267	0.9103389158984166	0.3626438012071089	1.0	0.5999399238086617	43	O43169,Q16850,Q9NUJ1,P16435,Q8TB61	5
G alpha i signalling events	0.3970501029795159	0.9051974561442492	0.3653607893103165	1.0	0.6029973550091788	23	Q9UBI6,P04083,Q9NZJ7,O43865,P30153,P52292,P30154,P07602	8
Signaling by gpcr	0.345424464272268	0.9015986690589484	0.3672700982908821	1.0	0.6044032393839871	42	O00459,Q8N2K0,P04083,Q9NZJ7,O43865,P42892,P30153,P52292,P30154,O60658,P07602,Q9Y3E5,Q15418	13
Diseases associated with glycosylation precursor biosynthesis	0.5231394439916999	0.8971096174942302	0.3696604272492838	1.0	0.6057717509114592	8	P10619	1
Apoptotic factor mediated response	0.5112647430133292	0.8941150410609898	0.3712603424818246	1.0	0.6069603714543846	5	Q9NR28	1
Carboxyterminal post translational modifications of tubulin	0.5097911227154057	0.8866794448160649	0.375251508071468	1.0	0.6127636390625855	5	Q14166,Q9BVA1,Q13509,P68371	4
Aurka activation by tpx2	0.371263484754284	0.8840396820738459	0.376674792030913	1.0	0.6143649956978934	30	P62258,P53350,Q13561,Q15154,O94927,Q9H6D7,O75935,Q7Z4H7,P30153,O43805,O95684,P41208,P07900	13
Activation of nima kinases nek9 nek6 nek7	0.4711423847024871	0.872295335370746	0.383047281716975	1.0	0.6213953236862668	4	P53350	1
Adenylate cyclase inhibitory pathway	0.3981089012063832	0.8630962541300892	0.3880845473104641	1.0	0.625622940379703	2	P04899	1
Ub specific processing proteases	0.3167987476373166	0.8434363798007396	0.3989844328313867	1.0	0.6358020941200287	69	P28072,P21796,Q9Y277,P49720,P45880	5
Beta catenin phosphorylation cascade	0.52502055589429	0.8424060691338404	0.3995606970067384	1.0	0.6358020941200287	7	P30153,P30154	2
Disassembly of the destruction complex and recruitment of axin to the membrane	0.52502055589429	0.8424060691338404	0.3995606970067384	1.0	0.6358020941200287	7	P30153,P30154	2
Signaling by ctnnb1 phospho site mutants	0.52502055589429	0.8424060691338404	0.3995606970067384	1.0	0.6358020941200287	7	P30153,P30154	2
Platelet activation signaling and aggregation	0.3128195697561461	0.8418075279284429	0.3998956975265022	1.0	0.6358020941200287	58	O00459,Q8NBX0,Q92520,O15439,O94919,Q9Y6I9,Q8N2K0,O43852,Q9NZJ7,Q9NUQ9,P46108,Q08380,Q6UXV4,P07602,P13473,Q96JJ7	16
Postmitotic nuclear pore complex npc reformation	0.3883657590003737	0.8396719644078289	0.401092337356254	1.0	0.6369750163048977	23	Q8NFH5,Q8NFH4,Q9BTX1	3
Anchoring of the basal body to the plasma membrane	0.3630014933060884	0.8288444615467174	0.4071924256026791	1.0	0.640797150494919	31	P62258,P53350,Q13561,Q15154,O94927,P06493,Q9H6D7,O75935,Q7Z4H7,P30153,O43805,Q15691,O95684,Q96CS2,P41208,P07900	16
Erythropoietin activates ras	0.4259621656881878	0.8205164217518303	0.4119217715584746	1.0	0.6436910419609502	3	P62993,P07948	2
Basigin interactions	0.5144268745844183	0.7907490114496767	0.4290904694115445	1.0	0.6618444576042548	7	P53985	1
Hemostasis	0.2822814726583028	0.789858079769908	0.4296106554605938	1.0	0.6618444576042548	124	Q9Y6I9,P30626,P07602,Q96JJ7,Q9UBI6,O15439,Q8N2K0,O43852,Q9NUQ9,P46108,P30154,Q07021,P42785,Q08722,P13473,O00459,P63104,Q92896,Q9NZJ7,P16615,Q9UNN8,Q6UXV4,P20020,Q8IWA4,Q8NBX0,P53985,Q92520,O94919,Q13586,P30153,Q08380,P45973,P35613	33
Slc transporter disorders	0.350771495761445	0.7717920874824441	0.440237578874437	1.0	0.6701270016406585	34	P53985,O00400,Q9BTX1,Q8NFH4,P35613	5
Interleukin 4 and interleukin 13 signaling	0.4383448230995436	0.7716630928306671	0.4403139953143231	1.0	0.6701270016406585	13	P09601,P08670	2
Platelet sensitization by ldl	0.4510765766990144	0.764970202436005	0.4442892883897049	1.0	0.6739601445736727	4	P30154	1
Abc transporter disorders	0.3281132004918536	0.7553212963135978	0.4500562236184899	1.0	0.6812192348772782	43	O75477,P28072,O94905,P49720,P49721,Q9BUN8	6
Defective cftr causes cystic fibrosis	0.3281132004918536	0.7553212963135978	0.4500562236184899	1.0	0.6812192348772782	43	O75477,P28072,O94905,P49720,P49721,Q9BUN8	6
Activation of bad and translocation to mitochondria	0.5040097916891376	0.740222611180293	0.4591649297626583	1.0	0.6904885400981254	7	P62258,P27348,P63104,P61981,P31946	5
Maturation of sars cov 1 spike protein	0.4450244698205574	0.7328481927260582	0.4636510240631923	1.0	0.6934780403014128	4	P27824,Q14697,P14314	3
Downstream signaling events of b cell receptor bcr	0.3248694149024039	0.7230710565191075	0.4696362302396943	1.0	0.7001665817107365	43	P62942,P49720,P28072	3
Metabolism of folate and pterines	0.4996255572166899	0.7190540980218924	0.4721075880687508	1.0	0.7030958500423028	7	P00374	1
Intra golgi traffic	0.423424130799197	0.715057977131689	0.4745732190643288	1.0	0.7042846277978785	14	O95249,Q8TBA6,O00461	3
Orc1 removal from chromatin	0.2989965983289326	0.6877575998347133	0.4916054408695158	1.0	0.7197767425389114	51	Q9Y619,P49720,P49721,P28072	4
Ptk6 expression	0.3687642647538248	0.6825070300718828	0.4949183990167283	1.0	0.7215827078101038	2	P04150	1
Plasma lipoprotein assembly remodeling and clearance	0.4001168111413112	0.6794084670968549	0.4968790864690089	1.0	0.7222168243283937	17	O15118,P35610,Q8WTV0,P07237	4
Signalling to erks	0.4549190233081798	0.679352855816564	0.4969143135688876	1.0	0.7222168243283937	10	P46108	1
Recruitment of mitotic centrosome proteins and complexes	0.3417615592431803	0.6624392318979149	0.5076897677679328	1.0	0.7317480764920984	32	P62258,P53350,Q13561,Q15154,O94927,Q9H6D7,O75935,Q7Z4H7,P30153,O43805,O95684,P41208,P07900	13
Plasma lipoprotein clearance	0.4204824457723006	0.6371577716729344	0.5240220808644314	1.0	0.749837781690547	12	O15118,P35610,Q8WTV0	3
Apoptotic cleavage of cellular proteins	0.3804591239856322	0.6337485564629578	0.5262449307789616	1.0	0.7506273817204838	19	P49354,Q16625,P08670,P51572	4
Signaling by erythropoietin	0.4261011419249566	0.6334627713628675	0.5264314847724938	1.0	0.7506273817204838	4	P19174,P62993,P07948	3
Visual phototransduction	0.4566820113453129	0.6229364030847316	0.5333263148426775	1.0	0.7583413809099396	9	P49356,Q6NUM9,P49354	3
Nod1 2 signaling pathway	0.4238172920065131	0.6215973123809868	0.5342066887076107	1.0	0.7583413809099396	4	Q13685,P61088,Q96J02	3
Activation of ampk downstream of nmdars	0.4543080939947724	0.6109679078324419	0.541220826343654	1.0	0.7650281494349619	5	Q13885,Q9BVA1,Q13509,P68371	4
Heme biosynthesis	0.4868878762153934	0.6076657663959356	0.5434091724060854	1.0	0.7658389640570755	6	P22830	1
Signaling by the b cell receptor bcr	0.3026127713796416	0.6005821513379719	0.5481183289752567	1.0	0.7715905077258177	47	P62942,P49720,P28072	3
Cyclin a b1 b2 associated events during g2 m transition	0.4510756164741797	0.5945484533588582	0.5521453448065072	1.0	0.7755376354454323	9	P30153,P30154	2
P75 ntr receptor mediated signalling	0.4383250199035076	0.5916365325047386	0.5540940049226841	1.0	0.7756920108681731	10	Q9NQC3	1
Extracellular matrix organization	0.3350131124452489	0.5816286213431284	0.5608168599294325	1.0	0.7815546418861408	30	O75718,Q92542,P07942,P07237,O15460,P55081,P13674,P35613,Q08722,Q32P28	10
Nuclear envelope ne reassembly	0.3033740098319498	0.5816129853095424	0.5608273943217552	1.0	0.7815546418861408	46	Q9BTX1,Q14739,Q8NFH5,P30153,Q8NFH4,P50402,Q86XL3,P42167	8
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein	0.377068408949316	0.5696006063018808	0.5689486171493803	1.0	0.791283247097535	18	P10619,Q9BT22,P16278,Q2TAA5	4
Sumoylation of rna binding proteins	0.329066091787583	0.5681871494405103	0.5699078963085651	1.0	0.7918239840603487	33	Q8TEM1,P61978,P07910,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q99496,Q8IXK0,Q8N1F7	11
Signaling by wnt in cancer	0.4562562915721849	0.5640676902733952	0.5727080657321229	1.0	0.7941246705656209	8	P30153,P30154	2
Mtor signalling	0.4074615370124202	0.5630704818005189	0.5733868907644428	1.0	0.7942724594621224	12	P62942	1
Ctla4 inhibitory signaling	0.4434639551617436	0.5586405132451713	0.5764070849471841	1.0	0.7976600537454551	5	P30154	1
Negative regulation of nmda receptor mediated neuronal transmission	0.4536434781114621	0.5514602450718364	0.5813182118718578	1.0	0.8012608521133452	8	P07196	1
Tgf beta receptor signaling activates smads	0.451510530747082	0.5412011358952108	0.588368954653052	1.0	0.8093717631897285	8	P62942	1
Signaling by fgfr1 in disease	0.4270824507278913	0.533180467523103	0.5939086611377737	1.0	0.8153760847272304	10	O94905	1
Fgfr1 mutant receptor activation	0.4385257495566448	0.5317104612651365	0.5949265453329542	1.0	0.8154356454763547	9	O94905	1
Neutrophil degranulation	0.27170885083956	0.5295568819865613	0.596419196283331	1.0	0.8155568180640643	173	Q9Y376,Q9NQX7,P30519,O00264,P10619,P07602,Q93050,Q13510,P42785,O00584,P10253,O15260,Q9NZJ7,P16278,P10321,Q8NF37,P06280,Q9H7Z7,Q07065,P17900,Q9BTY2	21
Recruitment of numa to mitotic centrosomes	0.3210585210463695	0.5280043156856169	0.5974963405634028	1.0	0.8155568180640643	35	P62258,P53350,Q13561,Q15154,O94927,Q9H6D7,O75935,Q7Z4H7,P30153,O43805,O95684,P41208,P07900	13
Activation of bh3 only proteins	0.4256292906178603	0.5256923677085319	0.5991019675853684	1.0	0.8160486074666253	10	P62258,P04637,Q96FJ2,P27348,P63104,P63167,P61981,Q9Y3B8,P31946	9
Insulin processing	0.4129615200847525	0.5230237572161556	0.60095772081154	1.0	0.8175121077150705	11	Q8TAD4,Q8NEW0	2
Antigen processing cross presentation	0.2836318262256868	0.5165321340843169	0.605482801489015	1.0	0.8215152770936001	51	P20618,P28072,Q03519,P28070,P49721,P04439,P49720,Q9UIQ6,P10321	9
Intrinsic pathway for apoptosis	0.371883180456472	0.4999178222976257	0.6171329424799825	1.0	0.8332495371227779	17	P62258,P30419,P04637,P27348,P63104,Q07021,P98170,Q9NR28	8
Gaba b receptor activation	0.398368678629685	0.4918781164048504	0.6228055093182989	1.0	0.835834665330293	4	Q9UBI6,P04899,P63218	3
Gaba receptor activation	0.398368678629685	0.4918781164048504	0.6228055093182989	1.0	0.835834665330293	4	Q9UBI6,P04899,P63218	3
Adp signalling through p2y purinoceptor 12	0.398368678629685	0.4918781164048504	0.6228055093182989	1.0	0.835834665330293	4	Q9UBI6,P04899,P63218	3
Cdt1 association with the cdc6 orc origin complex	0.3050088061239084	0.4887482719765297	0.625019924014395	1.0	0.8373819059188998	41	Q9Y619,P49720,P28072	3
G2 m dna replication checkpoint	0.3348549070753198	0.4815674975144277	0.6301132199831292	1.0	0.8425791419427585	2	P06493	1
Post translational modification synthesis of gpi anchored proteins	0.4580825944394479	0.4783511391873095	0.6324003038996553	1.0	0.8446623119448388	6	O43292,Q9H490	2
Synthesis of pips at the golgi membrane	0.4259581184070989	0.4758619163180695	0.6341727555290877	1.0	0.8446623119448388	5	Q10713	1
Regulation of plk1 activity at g2 m transition	0.3148258386533243	0.474304951495879	0.635282461105684	1.0	0.8446623119448388	35	P62258,P53350,Q13561,Q96CV9,Q15154,O94927,Q9H6D7,O75935,Q7Z4H7,P30153,O43805,O95684,P41208,P07900	14
Switching of origins to a post replicative state	0.283026314289727	0.4733956688682363	0.6359309192956459	1.0	0.8446623119448388	61	P30260,Q9Y619,Q9UJX4,Q14566,P20618,Q9UJX3,Q96DE5,P28072,P28070,P49721,P49720	11
Sumoylation of sumoylation proteins	0.3239191743714385	0.4680037579102038	0.6397819023482441	1.0	0.8478171744210348	27	Q8TEM1,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q8N1F7	7
Regulation of glucokinase by glucokinase regulatory protein	0.3239191743714385	0.4680037579102038	0.6397819023482441	1.0	0.8478171744210348	27	Q8TEM1,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q8N1F7	7
Met activates ptk2 signaling	0.359505640726395	0.4514700880019435	0.6516507787765693	1.0	0.8581114970524871	3	P07942	1
Tp53 regulates metabolic genes	0.3163184395623798	0.4497965273806288	0.6528571620226415	1.0	0.8581114970524871	32	Q8N8Q8,O43819,P20674,P63104,P00403,P13073,O75880	7
Phosphorylation of the apc c	0.3804155822451048	0.4359785983107987	0.6628522574203555	1.0	0.8704247240297572	13	P30260,P53350,Q9UJX4,Q96DE5	4
Dap12 interactions	0.4476171073521554	0.432767017153393	0.6651840371743212	1.0	0.8710145694320357	6	O00459,P62993,P10321	3
Translation of sars cov 1 structural proteins	0.4369693011103987	0.4268197499416873	0.6695106202024086	1.0	0.8742057768964658	7	Q10472,P14314,Q13724,P27824,Q14697,P49841	6
Retrograde transport at the trans golgi network	0.3686588642379643	0.4197117694919089	0.6746960261303734	1.0	0.8757657303821044	15	Q8N1B4,Q8N2H4,P51151,Q5VZE5,P40616	5
Intraflagellar transport	0.3928693643552874	0.417396872770463	0.67638814189406	1.0	0.8757657303821044	11	A0AVF1	1
Deubiquitination	0.2833741527134139	0.4126367925359657	0.6798727406544356	1.0	0.8757657303821044	87	P28072,P21796,Q8NB78,Q9Y277,P49720,P45880	6
Apc cdc20 mediated degradation of nek2a	0.3761457920495969	0.4124428838183602	0.68001483647284	1.0	0.8757657303821044	13	P30260,Q9UJX4,O60566,Q96DE5	4
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.3761457920495969	0.4124428838183602	0.68001483647284	1.0	0.8757657303821044	13	P30260,Q9UJX4,O60566,Q96DE5	4
Pyruvate metabolism	0.3519302133168858	0.4097699137598736	0.6819747383318155	1.0	0.876926919155234	18	P53985,P21796	2
Antigen presentation folding assembly and peptide loading of class i mhc	0.3562814419346096	0.4043204464338423	0.6859770919444701	1.0	0.8807920477510865	17	P10321,Q03519,Q6P179,P04439,Q9NZ08,P51572	6
Wax and plasmalogen biosynthesis	0.3791190864600298	0.3976670377038766	0.6908756379287087	1.0	0.8854435692013367	4	Q8WVX9,O00116,O15228	3
Regulation of tp53 expression and degradation	0.4189555286050936	0.3890322317453097	0.6972523033127787	1.0	0.8875776098457634	8	P30154	1
Beta oxidation of butanoyl coa to acetyl coa	0.3772669572419359	0.3888228253633449	0.6974072146770478	1.0	0.8875776098457634	4	Q16836	1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.2691479836635825	0.3884859301113484	0.6976564642231469	1.0	0.8875776098457634	52	P30260,P53350,Q9UJX4,P20618,Q9UJX3,Q96DE5,P28072,P28070,P49721,P49720	10
Uptake and function of anthrax toxins	0.3460534898891018	0.3818467402637995	0.7025750471964203	1.0	0.8921996024781622	3	Q8WUM4,Q02750	2
Non integrin membrane ecm interactions	0.4221042744838307	0.3617330587293243	0.7175515203447325	1.0	0.902267822003412	7	Q14118,O14936,P07942,P05556,P12814	5
Interleukin 3 interleukin 5 and gm csf signaling	0.4031766135226485	0.3616996130806584	0.7175765162241221	1.0	0.902267822003412	9	O00459,P46108	2
Pi metabolism	0.362445745542595	0.360006708446999	0.7188421168511183	1.0	0.902267822003412	14	Q10713,P48739,Q9NZC3,Q9NTJ5	4
Ion homeostasis	0.366091391565834	0.3384178681833949	0.7350483107946042	1.0	0.9116297236377504	12	P05023,Q13586,P16615,O43865,P20020	5
Sumoylation of ubiquitinylation proteins	0.3058532413905409	0.3365551429973472	0.7364522759928818	1.0	0.9116297236377504	28	Q8TEM1,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q8N1F7	7
Hedgehog ligand biogenesis	0.2847725807368195	0.3033742236387873	0.7616046871720523	1.0	0.9330161569239264	41	P49720,P49721,P28072	3
Negative regulation of mapk pathway	0.3691714691183393	0.2989407132087399	0.7649852820203469	1.0	0.93342981820967	11	P30153,P30154	2
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex	0.3886686802992668	0.2958791812519523	0.7673223505599664	1.0	0.93342981820967	9	P62258,P27348,P63104,P06493,P61981,P31946	6
Thromboxane signalling through tp receptor	0.3851174934725982	0.2939998006743937	0.7687580556835594	1.0	0.9339395014690908	5	Q13685,Q9UBI6,P29992,P63218	4
Nuclear pore complex npc disassembly	0.2965627384095359	0.2784868132325978	0.7806386863501258	1.0	0.9422828098866974	30	Q8TEM1,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q7Z3B4,Q8N1F7	8
Neurotransmitter release cycle	0.408978635334154	0.2733563946275433	0.7845792687265303	1.0	0.9449900446476996	6	Q96QD8	1
Interleukin 7 signaling	0.3222439660795826	0.265511688869063	0.7906153064855848	1.0	0.950107398616443	3	O00459,P51532	2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase	0.3717665466993835	0.2635644327603073	0.7921155681945637	1.0	0.9502648302973676	10	P30260,Q9UJX4,Q96DE5	3
Depolymerisation of the nuclear lamina	0.3587793365611842	0.249642993203142	0.8028634472408931	1.0	0.9606676420434136	11	P50402	1
Mitotic g1 phase and g1 s transition	0.2690660288582758	0.2467122549146722	0.8051309216383329	1.0	0.9611341527274622	73	Q9Y619,Q14566,P28072,P49720,P00374,P28070,P49721,P30154,P31350	9
Degradation of beta catenin by the destruction complex	0.2637892821860342	0.2306917511277696	0.8175542823437263	1.0	0.969154066878449	48	P25054,P20618,P28072,P28070,P30153,P49721,P30154,P49720	8
Interleukin 12 signaling	0.2904963623415005	0.2219475654670617	0.8243547019316448	1.0	0.9737909159839344	27	O00170,P52597,P07237,P22626,Q13126,O14979,Q9UL46,P78417	8
Miscellaneous transport and binding events	0.3940541461939599	0.2164683911694702	0.8286226612502898	1.0	0.974024610322158	6	Q8TDW0	1
Signal amplification	0.3853690398432391	0.2118417827337794	0.8322304702980303	1.0	0.9751613288487776	7	Q9UBI6,P04899,P63218,P29992,P08754,Q13685	6
Ca2 pathway	0.3838502799095385	0.2060448642943337	0.8367558664689438	1.0	0.9751613288487776	7	Q9UBI6,P09471	2
Chaperone mediated autophagy	0.3828073781103555	0.202084879833454	0.8398503681529881	1.0	0.9771268323523448	7	P13473,P08670	2
Cargo trafficking to the periciliary membrane	0.3059807433423468	0.1950398686406744	0.8453617362552031	1.0	0.9814545326237424	20	Q10713,O43924,A6NIH7	3
Activation of kainate receptors upon glutamate binding	0.3603133159269026	0.1941672912309061	0.84604489326253	1.0	0.9814545326237424	5	Q9UBI6,P63218,Q12959,Q92796	4
Export of viral ribonucleoproteins from nucleus	0.2847084573926575	0.1881027613779999	0.8507960964713177	1.0	0.9814545326237424	29	Q8TEM1,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q8N1F7	7
Suppression of phagosomal maturation	0.3781841933376834	0.1847366922985512	0.8534355651864924	1.0	0.9822293237801422	7	P52294,P20339,Q9UI12,Q9H267,P51149,O14964	6
Sumoylation of chromatin organization proteins	0.2779645161027458	0.1833171267591493	0.8545491968917494	1.0	0.9823112124520856	36	Q8TEM1,Q15022,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q99496,P45973,Q8IXK0,Q8N1F7	11
Ns1 mediated effects on host pathways	0.2782715471272044	0.1689331677531615	0.8658492100260191	1.0	0.9932220690215824	34	Q8TEM1,Q9NRG9,Q99567,Q8NFH5,P52292,Q9BTX1,Q8NFH4,Q8N1F7	8
Mitotic telophase cytokinesis	0.3493757152942127	0.1668904328763125	0.8674562610349694	1.0	0.9939843745510466	10	Q9Y6X3	1
Fgfr2 alternative splicing	0.3306127257123093	0.1662098849144071	0.8679917806137369	1.0	0.9939843745510466	12	P52597	1
Mitotic spindle checkpoint	0.2534034680696807	0.1653580921817607	0.8686621371256624	1.0	0.9939843745510466	58	P30260,Q6IPU0,P53350,Q9UJX4,O60566,Q9UJX3,Q96DE5,Q15005,P30153,Q2NKX8,Q8NFH4,Q9HBM1,Q6P1K2,P30154	14
Collagen formation	0.3262823294087318	0.1592931857846355	0.8734378891692351	1.0	0.9986258568096362	13	P13674,P07237,Q32P28,O15460	4
Activation of atr in response to replication stress	0.305934661194942	0.1455650678099058	0.8842647460376867	1.0	1.0	18	Q9Y619	1
Uch proteinases	0.2563582367677726	0.1416855244441005	0.8873284094020439	1.0	1.0	47	P49720,Q8NB78,P28072	3
Ripk1 mediated regulated necrosis	0.3337550382276121	0.1392089589684443	0.8892850292057342	1.0	1.0	11	Q8WUM4,Q13546,Q16543,P41440,P07900	5
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.3702252693437856	0.1324361795099721	0.8946392995837922	1.0	1.0	6	Q9NZN8,P04637,P06748,Q92600,A5YKK6	5
Alpha linolenic omega3 and linoleic omega6 acid metabolism	0.3607207114350483	0.1224334211207215	0.9025557713762152	1.0	1.0	7	O14734,Q15067	2
Apc c cdc20 mediated degradation of cyclin b	0.3201994218111247	0.120690835904633	0.9039359178226049	1.0	1.0	12	P30260,Q9UJX4,Q96DE5	3
Nuclear import of rev protein	0.2738112918369521	0.1205689864944647	0.904032434787839	1.0	1.0	31	Q8NFH4,Q9BTX1	2
Interleukin 12 family signaling	0.2742074096254167	0.1197317474879217	0.9046956504001205	1.0	1.0	30	O00170,P11233,P52597,P07237,P22626,Q13126,O14979,Q9UL46,P78417	9
Regulation of lipid metabolism by pparalpha	0.3099242894545964	0.1121612160046125	0.9106955802186492	1.0	1.0	15	P37268,P50416,Q15067,P23786	4
Nuclear envelope breakdown	0.260549531038663	0.1085323598213073	0.9135734126884758	1.0	1.0	42	P53350,Q9BTX1,Q8NFH5,Q8NFH4,P50402	5
Transferrin endocytosis and recycling	0.3232175275943534	0.0967552056631317	0.9229207976647968	1.0	1.0	11	Q93050,P02786,Q15904,Q9Y5K8	4
Signaling by braf and raf1 fusions	0.2772633307077069	0.0932669144763058	0.9256915159052772	1.0	1.0	24	P51114,Q9NRY5	2
Egfr downregulation	0.3517308948399681	0.0925011092658792	0.9262999099343684	1.0	1.0	7	P42566,Q92783,Q9Y6I3,O14964,P60953,P62993	6
Regulation of runx3 expression and activity	0.2629358287664587	0.0873754507102557	0.930373082230742	1.0	1.0	38	P49720,P28072	2
Interactions of vpr with host cellular proteins	0.265929313668721	0.0804196378558048	0.9359035087374434	1.0	1.0	34	Q8TEM1,P12236,Q9NRG9,Q99567,Q8NFH5,Q9BTX1,Q8NFH4,Q7Z3B4,P12235,Q8N1F7	10
Ldl clearance	0.3270346374118487	0.0803933125579516	0.9359244454964686	1.0	1.0	10	O15118,P35610	2
Degradation of axin	0.2618798644179538	0.0795195540362503	0.9366193789889092	1.0	1.0	38	P49720,P28072	2
Cross presentation of soluble exogenous antigens endosomes	0.2618798644179538	0.0795195540362503	0.9366193789889092	1.0	1.0	38	P49720,P28072	2
Apc c mediated degradation of cell cycle proteins	0.2467446877270198	0.079486482935401	0.9366456826490206	1.0	1.0	60	P30260,P53350,Q9UJX4,O60566,P20618,Q9UJX3,Q96DE5,P28072,P28070,P49721,P49720	11
Stabilization of p53	0.2594119512493559	0.0702508473125777	0.9439940039565736	1.0	1.0	39	P49720,P28072	2
Cobalamin cbl vitamin b12 transport and metabolism	0.2992873767319642	0.0684335173350635	0.9454405413844472	1.0	1.0	4	Q9H3L0	1
Defects in cobalamin b12 metabolism	0.2992873767319642	0.0684335173350635	0.9454405413844472	1.0	1.0	4	Q9H3L0	1
G1 s dna damage checkpoints	0.2574117877946992	0.0650327450379095	0.9481479286583364	1.0	1.0	40	P49720,P28072	2
Signaling by alk	0.3224543080939998	0.0629354797330411	0.9498178820916918	1.0	1.0	5	O00459,P19174,Q96ST3,Q92769	4
Degradation of the extracellular matrix	0.3390779988408539	0.0530380308926354	0.95770160607215	1.0	1.0	7	P35613,Q92542	2
Rhoj gtpase cycle	0.2789797995154984	0.0504487449866696	0.9597647929291622	1.0	1.0	20	O00459,Q9Y6M7,P42167,Q15758	4
Assembly and cell surface presentation of nmda receptors	0.3106262856652725	0.0495995097473949	0.960441537317724	1.0	1.0	11	P07196,O14936	2
Death receptor signalling	0.2913248708981969	0.0436315607213885	0.9651980938275764	1.0	1.0	16	Q9NQC3	1
Degradation of dvl	0.2553862527051635	0.0405141387022737	0.9676832352420026	1.0	1.0	39	P49720,P28072	2
Intra golgi and retrograde golgi to er traffic	0.2541274378601809	0.0332080683317958	0.973508664074143	1.0	1.0	88	Q8TBA6,Q8N2H4,O15498,Q9H0U4,Q5VZE5,O95249,Q9NSK0,Q10471,Q9Y3B3,P51151,O00461,P40616,P49755,Q12981,O15260,O75935,Q6NUQ1,Q10472,Q8N1B4,Q9P2W9,Q13190	21
Metabolism of polyamines	0.2530812198497715	0.0326232681835633	0.9739750143769212	1.0	1.0	40	P49720,P28072	2
Asymmetric localization of pcp proteins	0.253998237029937	0.0304614495878279	0.9756990378757348	1.0	1.0	39	P49720,P28072	2
Erks are inactivated	0.3285770436776441	0.0227806110782063	0.981825274129876	1.0	1.0	7	P30154	1
Erk mapk targets	0.3158757165345041	0.0196017849665287	0.9843610399103128	1.0	1.0	9	P30153,P30154	2
Mapk targets nuclear events mediated by map kinases	0.3158757165345041	0.0196017849665287	0.9843610399103128	1.0	1.0	9	P30153,P30154	2
G protein beta gamma signalling	0.2822185970636252	0.0160984551737417	0.9871558459488724	1.0	1.0	4	Q9UBI6,P60953,P63218	3
G beta gamma signalling through cdc42	0.2822185970636252	0.0160984551737417	0.9871558459488724	1.0	1.0	4	Q9UBI6,P60953,P63218	3
Syndecan interactions	0.3049310240378283	0.0124619708376413	0.9900570432301894	1.0	1.0	5	P12814,O14936,P05556	3
Regulation of pten stability and activity	0.2471860267683917	0.0042173126931473	0.99663508128865	1.0	1.0	42	P49720,P28072	2
Pyruvate metabolism and citric acid tca cycle	0.2534230276988971	0.001754944703059	0.9985997574351182	1.0	1.0	35	P21912,P21796,P53985	3
The role of gtse1 in g2 m progression after g2 checkpoint	0.2368414476874045	0.0010190210994032	0.999186938938368	1.0	1.0	49	P53350,P20618,P28072,P28070,P49721,P49720	6