term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 Transmembrane transport 86 219 5.152130973492186 2.575430598014111e-07 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 1.3662442946522366e-09 2.684122498122876e-08 7.83408135465965e-09 3.4215393937487457e-10 2.6427061106972003e-14 Mitochondrion organization 64 186 5.0164193276613 5.264336578856604e-07 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 1.9027404739351733e-12 8.367828938374419e-08 1.593748864666441e-07 8.3375436333063e-11 1.6022307331419104e-16 Ion transmembrane transport 68 161 4.471389436279214 7.771303440540223e-06 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 3.621402459090692e-06 8.07603052041246e-06 7.431974486696803e-06 2.0040734680412047e-06 2.297041502412207e-09 Mitochondrial transport 35 85 4.44331182238809 8.85846354092834e-06 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 2.1689498788159543e-11 5.642269789799035e-09 7.709318440132988e-08 1.645460919215726e-11 1.5635849723129264e-13 Membrane lipid metabolic process 21 36 4.396798754026555 1.098591149384376e-05 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 1.1261608854598476e-09 0.0197758267942588 0.0010779549165811 1.964351487934708e-07 5.8196789450259134e-08 Sphingolipid metabolic process 20 28 4.319691441499002 1.5624751315224117e-05 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 9.442963169729404e-11 0.0102936075696032 0.0002941410216948 5.421900558766083e-08 2.938383476078935e-09 Ion transport 82 210 4.192234606790338 2.7622012676031812e-05 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 4.706344540978937e-06 3.252372574888117e-05 3.23569862826947e-05 1.0150440327795252e-05 1.549014059133997e-07 Mitochondrial transmembrane transport 28 52 4.07199052663676 4.661307562936479e-05 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 2.6653980828128623e-06 2.947739650573756e-06 1.5443406323716429e-06 8.964213844581752e-07 2.674658035174025e-09 Cation transmembrane transport 48 124 4.023692003614907 5.729283408340002e-05 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0009124183749616 0.0086344442231225 0.0033357135019959 0.0019435973721331 1.1875487564772356e-05 Membrane organization 79 220 3.98126916493137 6.854827128943697e-05 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 8.267385845489998e-07 0.0399875865627003 0.0133359771981713 3.3299978376645685e-05 1.903353331710605e-11 Cation transport 56 159 3.906804661033654 9.352470081136488e-05 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.0025183004634181 0.0091015487948617 0.0030538143590231 0.0048067529347462 0.0003006417213413 Protein localization to mitochondrion 26 61 3.884752382031229 0.0001024342351374 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.5910438489586315e-10 7.327182402218247e-07 9.407244365751534e-06 6.408685627835977e-09 8.937219572000681e-13 Mitochondrial membrane organization 21 48 3.860700796133539 0.0001130622838432 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 1.976224782072435e-06 0.0011305823171669 0.0023726768380501 2.0088787084628445e-05 7.317389282109348e-10 Protein targeting 38 108 3.8474433639518177 0.0001193568572301 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 4.360929035567646e-07 2.271471423927721e-05 5.2725611662735375e-06 1.1363322771402856e-05 1.13775194423214e-09 Protein targeting to mitochondrion 21 48 3.7536356765110366 0.0001742881266302 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 1.4834057400716528e-08 1.79356702812789e-07 2.0140068816332977e-06 1.808259587286089e-07 1.1965326430489856e-10 Mitochondrial respiratory chain complex assembly 14 41 3.6986923673835 0.000216713071482 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 1.0191928490835917e-06 0.0009257347283437 0.0018751862862679 6.892127383073779e-05 6.651802149315022e-06 Anion transmembrane transport 32 44 3.696156490313157 0.0002188880813021 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 0.0008886344861538 0.0019982551464922 0.0046116462239443 0.0003886147726859 3.652935394730274e-07 Inorganic ion transmembrane transport 37 118 3.678139783343588 0.0002349411988058 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0014357626461795 0.0002000125025504 0.0004633897943059 0.0017269528522919 5.370874672582162e-05 Membrane lipid biosynthetic process 11 23 3.666262086953796 0.0002461216838345 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 1.034861566374411e-05 0.3274019772455256 0.0453414776018772 0.0008257473825444 0.0005580518501476 Organophosphate ester transport 18 29 3.655298661514316 0.0002568827467301 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0008980191984192 1.0 0.0009958002736197 0.0006433942897512 2.8859453983321405e-08 Ceramide metabolic process 13 19 3.635902798934029 0.0002770087766701 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 1.979875200533551e-08 0.2406936845278361 0.0177960185678587 8.368334725673228e-06 3.768973044350322e-07 Endoplasmic reticulum organization 19 40 3.623776942929748 0.0002903320157248 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 0.0001425032338401 0.3075216202298709 0.1682749782688163 0.0024265102629424 2.910136880526074e-06 Anion transport 33 73 3.5680489004034035 0.0003596493932478 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 2.1411643879132204e-05 0.0003660463043171 0.0032691237730569 0.0001075162928924 2.9743059482837436e-08 Oxidative phosphorylation 16 59 3.568019564468256 0.0003596896526272 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 0.0001060946096043 0.0024928514015356 0.0059539422475933 0.0001468869191914 5.765870451118338e-05 Sphingolipid biosynthetic process 10 17 3.489254083324864 0.0004843705063224 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 2.1388671475080837e-06 0.2480154974279715 0.0195000915431133 0.0005369188903581 0.0001061774836938 Organic anion transport 24 49 3.488140641241129 0.0004863921604556 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 0.0022109512601779 0.1520007577137938 0.1642923571168563 0.0242720779238094 3.990985325408788e-07 Localization within membrane 50 183 3.4108786117092245 0.0006475391295193 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 0.0003573453602123 0.0270276045374723 0.0183284857370795 0.0033419985098482 3.338988017254993e-06 Protein insertion into membrane 16 30 3.375925194223575 0.0007356791884256 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 4.575137515834678e-07 0.0018472853800074 0.0001285725065499 3.2137617365813383e-06 8.28667164925179e-08 Establishment of protein localization to membrane 31 89 3.3747227913471978 0.0007389007959814 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 2.827163034442189e-05 0.0163421355973242 0.0036470065281125 0.0004543362831904 5.723210044964655e-07 Carbohydrate derivative transport 15 19 3.2585509831456254 0.0011198275300812 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0032497471990674 0.1991580424676108 0.0733374275738533 0.0049696490954306 1.6583857576792126e-07 Respiratory electron transport chain 14 50 3.243094682809501 0.0011823891084403 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 0.0002349665851591 0.0108990791164893 0.0664874170634557 0.0005293712950596 5.471666537932621e-05 Lytic vacuole organization 8 22 3.21295121663725 0.0013137860240608 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 0.0001097613724778 0.0335548880884004 0.0026898131037284 1.2904288255979382e-05 0.0022571444000092 Inner mitochondrial membrane organization 13 22 3.205570459251714 0.0013479504091957 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 1.764680781030786e-06 0.0135379522122687 0.0054315442599267 0.0002406237069856 7.341638285000007e-10 Atp synthesis coupled electron transport 11 38 3.150051801405758 0.001632415156247 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 0.0008182261916422 0.006163378346249 0.0400324838097305 0.0028146723122289 0.0003488465827906 Nitrogen compound transport 180 577 3.097901501088142 0.0019489619425161 134.15533980582524 569.4538834951456 0.9072063241864304 0.6401677607980054 37.1767641393764 58.81145048559368 1.470232145086419 0.4303798393104362 9.87518711194796e-05 0.012145230105151 0.0245264936484161 0.0001401176997676 4.2767559011000683e-07 Protein transmembrane transport 12 25 3.0873968537737166 0.0020191783211009 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0002530634639005 5.017816995023283e-06 1.1421997294757266e-05 0.0017183337360303 1.0029805990324731e-06 Carbohydrate derivative catabolic process 15 36 3.074103952798822 0.002111358492651 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 6.794423714253987e-05 1.0 0.0990612642216925 0.0004479491964386 0.0001173760982385 Vacuole organization 15 51 3.057200488827974 0.0022341478943106 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0109227580771 0.1706177828799348 0.0039291120395458 0.0013993416080422 0.0082876681361594 Proton transmembrane transport 17 43 3.0279383501053685 0.0024622831427036 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0008127601251625 0.0748187401998431 0.0131034302652722 0.000452953691518 0.0001635608273434 Carboxylic acid transport 15 35 3.0197889538594427 0.0025295087753414 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0063692528770971 0.0904452781629929 0.0820650305700749 0.0427349298488789 0.0001557499732073 Nadh dehydrogenase complex assembly 8 28 3.017391542039289 0.002549602590691 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 7.266525473015003e-05 0.0305319028295214 0.0177960185678587 0.0025056010914147 0.0003655904724143 Membrane lipid catabolic process 6 12 3.0155511624050524 0.0025651265909971 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 1.734550656342923e-06 0.0040679264544396 0.0158256043387446 5.674616226795717e-06 2.7180346417726147e-05 Establishment of protein localization to organelle 60 181 2.977126787629262 0.0029096365590188 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 2.859472689794787e-05 0.0002679591571988 0.0006635184993898 0.0001636565313312 2.1866159400404618e-07 Electron transport chain 18 68 2.971408278023226 0.002964374065576 19.550970873786408 67.77184466019418 0.3712062453977176 0.4872800905659868 8.486701420407794 5.37626783377928 1.3790913022045077 0.3735693075609537 8.012841103142381e-05 0.0253511637379553 0.0393903330921074 0.0003654441930061 1.918301656149602e-05 Ceramide biosynthetic process 6 11 2.927741170169 0.0034143414812082 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 9.95163264590742e-05 0.1553991536419083 0.0046396659223567 0.001461517407229 0.0012514150662819 Liposaccharide metabolic process 7 16 2.913440718970857 0.0035746970160293 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0004764593251172 1.0 0.4330643878145832 0.0131393408571549 0.0065824357934952 Regulation of mitochondrion organization 18 43 2.9036078447904345 0.0036888989815191 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0090751016872799 0.4158765777114258 0.0227342191395963 0.0056075608067222 0.0009277891216095 Protein maturation 21 65 2.892465857731425 0.0038223072335459 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0002419048757596 0.2515369543584532 0.1314882710724538 0.0012492417470269 0.0002965130771032 Ion homeostasis 37 108 2.8736476587042525 0.0040576135433982 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0201779355760612 0.0009642643500076 0.0424184398029792 0.0071444596915644 0.0059151757117277 Regulation of lysosomal lumen ph 2 5 2.8238774616628257 0.0047446520946399 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0110723766410014 0.0022827689145391 0.0090253131212995 0.005208827916976 0.0334620993119388 Mitochondrial electron transport ubiquinol to cytochrome c 1 5 2.81812517137583 0.0048304974420751 1.5048543689320388 4.206310679611651 0.8658650693935839 0.2665349265497743 0.9514810775456936 0.7935779738409815 1.3072925004771625 0.2886561243868636 0.0316229463164198 0.0007972103198291 0.0032139762811053 0.0189506401306209 0.0675218785318175 Aerobic respiration 15 83 2.8162476013825577 0.004858820429783 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 0.0001704925877063 0.0069963732250582 0.0191609623468548 0.0001312327472383 0.0002481209605599 Nucleotide transport 10 14 2.810430505016979 0.0049475272336374 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.048921629591182 1.0 1.0 0.1309570889500886 1.74740243519954e-07 Ceramide transport 2 5 2.7841960167399984 0.0053660594145514 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0072968442312668 0.0607401038440192 0.1191939669275513 0.0033939033653995 0.0225979674873623 Glycosphingolipid metabolic process 6 9 2.7761522303163546 0.0055006446757068 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 6.679472623092437e-05 1.0 0.2756599666896902 0.0080316637526189 0.0008647189955035 Sphingoid metabolic process 3 5 2.7527157790753787 0.0059103182988762 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0001849556739463 0.0470522829573702 0.0930016660897952 0.0015031185668187 0.0009118158302113 Response to oxidative stress 23 94 2.7424672645352786 0.0060979527712938 18.145631067961165 95.9757281553398 0.5057872201816154 0.5358657948719677 6.785060354870026 9.30128883458378 0.9511882590088212 0.3606217523881886 0.0129741240862902 0.0515614855824522 0.0237156920660862 0.0268355250245105 0.0084179909925968 Cytochrome complex assembly 7 13 2.7423436922212545 0.0061002475611444 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 8.183106879488519e-05 0.0115082778780227 0.0042717712834537 1.4200557955176332e-05 0.0001729005795719 Organic acid transmembrane transport 17 31 2.731345617305785 0.0063076285347949 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0138399534336496 0.3208381238265493 0.1821593613874541 0.0130864958075334 0.0004431313439272 Sulfur compound transport 6 11 2.729937380563157 0.0063346356767168 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0873926802316692 0.1471951297158956 0.0405463165390607 0.0453869127531283 0.0008647189955035 Purine nucleotide transport 9 13 2.721281938386962 0.0065029272891294 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 0.0246656034060207 1.0 1.0 0.0840389641709933 1.4497628230363953e-07 Chemical homeostasis 39 178 2.7153094700106 0.0066213864135944 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.0004561243094207 0.0164682670986013 0.0918271405541505 0.0004838928967102 0.0029453712228543 Steroid metabolic process 22 62 2.7099843493794813 0.0067286383031406 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 3.787350155515503e-05 0.5310682828592934 0.0651168132061343 0.0014738697279424 6.41910658057664e-05 Amyloid precursor protein metabolic process 8 22 2.699546127015909 0.0069434129658303 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0079165355623873 0.0285808600856777 0.0995728547031488 0.0105760203706863 0.0012031940780095 Lipid metabolic process 70 251 2.690877211529008 0.0071264419025947 70.49514563106796 273.7014563106796 0.4234492243219149 0.5257500979287635 24.98470358696109 28.74867152381156 1.6795947056521872 0.4126649977131845 8.793950381122634e-10 0.3218566559722789 0.0012981331240732 3.9119069216715974e-08 5.765466883577144e-09 Intracellular protein transmembrane transport 9 21 2.660401374123183 0.0078047581310627 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.002902296550369 0.0012844156650938 0.0009182879541791 0.0233376817152126 4.558635539447923e-05 Calcium ion import 8 12 2.6363592786417387 0.0083800950724193 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.0295583475963603 0.0007225305704933 0.0054315442599267 0.0120207550158922 0.0017617577033715 Endomembrane system organization 56 170 2.632899349883433 0.0084659431399112 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 0.0014566558086242 0.5601360273234894 0.1737632012102168 0.0134831548328626 2.574823958596928e-05 Sterol metabolic process 13 32 2.6235149499794965 0.0087027625618176 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 1.5080852794856972e-05 1.0 0.049541392930243 0.0010474863690053 5.3235976749312936e-05 Secondary alcohol metabolic process 11 35 2.60732467044347 0.0091252790007196 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 1.919908004456452e-05 1.0 0.0524436069866223 0.0012200675528821 0.0002690490900484 Inorganic anion transport 14 29 2.596388500799053 0.0094209476631814 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0015336411700322 1.855128547768521e-05 0.0005359635089116 0.0002540391317245 0.0004462881853716 Oligosaccharide metabolic process 2 5 2.593856913495259 0.0094905975464292 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 0.0357267845630647 1.0 1.0 0.0175758241055335 0.0981468657129251 Cellular respiration 16 99 2.581231336753829 0.0098448586105748 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 0.0001148471510257 0.0126559718977975 0.010112949625187 5.652590358108796e-05 0.0001216812374514 Vacuolar acidification 3 9 2.564796990755036 0.0103236187141564 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0022004305236781 0.0032958763634803 0.012905013470629 0.0007989256016515 0.0097510399506001 Phospholipid transport 5 15 2.5544020459816017 0.0106370354351474 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0054691760119087 1.0 0.0001285725065499 0.0014035458573663 0.0029392451780606 Cellular lipid metabolic process 55 191 2.5509673974667018 0.0107424374328308 55.06310679611651 205.83495145631068 0.2402431693065998 0.4937242414097398 20.280338607556292 23.717838556123585 1.6370289909336062 0.4061780961812439 4.5639755156425083e-08 0.1541029560306357 0.004688027105908 2.453149351553817e-06 8.311866242897782e-08 Regulation of release of cytochrome c from mitochondria 5 11 2.5463468354642287 0.0108856970673014 3.6310679611650487 10.805825242718448 0.7924389389582319 0.4006886058463786 1.815469081442188 1.3603843861930187 0.9712392086725492 0.3199873643457663 0.0753728904990679 1.0 0.0361556764775263 0.0387286577629364 0.0033138804057902 Organic acid transport 23 46 2.5451875227362897 0.0109219067413413 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0315358712150559 0.4854356723902606 0.3851788136583873 0.1171170078758993 0.0026185647469528 Cellular ion homeostasis 30 86 2.544670166541872 0.0109381002246697 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0554296920947302 0.0096723767157603 0.1261943205571607 0.0160212103209651 0.0135427981581155 Ceramide catabolic process 4 7 2.538627755309288 0.0111288162713292 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 2.1331113722936687e-05 0.0561990347849709 0.1105474823156849 0.0001450038876457 0.0001575214550341 Protein exit from endoplasmic reticulum 10 22 2.5166387078675334 0.0118480253445583 7.002427184466019 21.233009708737864 0.6943602976218084 0.4745028866201709 3.210645812910548 2.182026685495945 1.0430444956616387 0.3507892727806736 0.0115228371433118 0.187449079081247 0.0651781855152293 0.0037016693244557 0.0168189007239576 Intracellular transport 158 543 2.515823261728145 0.0118754717438058 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 0.0001591217077415 0.0001617730155477 0.0007578719530568 7.002760087120659e-05 4.4163331916333845e-05 Alcohol biosynthetic process 10 33 2.5157621528714635 0.0118775308231955 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0001070290142703 0.0667099047189351 0.0104695800354931 0.0013144682510841 0.0010628219793773 Establishment of protein localization to mitochondrial membrane 9 19 2.499720430607589 0.0124291348298486 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 1.3082361946876995e-06 0.0002813337316999 0.0001236370465893 2.711253345591e-06 2.6557460223247744e-07 Amino acid transmembrane transport 12 16 2.474530664745176 0.0133411367294631 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.4461918701132312 1.0 1.0 0.6865067343299582 0.0252009464097718 Peroxisomal transport 3 5 2.464339285339059 0.0137266106916578 2.4199029126213594 6.206310679611651 0.5152791591885746 0.4397608531291631 1.438341814396029 1.9279897928521967 0.9960993615772044 0.3114134157114668 0.132890879981864 1.0 1.0 1.0 0.0143001062154138 Establishment of protein localization 158 520 2.461072495404717 0.0138522372720011 118.26941747572816 516.7257281553398 0.6520395559374618 0.679532677582667 31.472560658738065 53.21298128179791 1.2523101724416292 0.4083128036600569 0.0001295330149566 0.01315167772046 0.0300062810058557 0.0001144411054305 3.356020633093213e-05 Organic hydroxy compound biosynthetic process 15 50 2.460405645173997 0.0138780058497782 12.42233009708738 52.37135922330097 0.7934054609743442 0.424605725297311 4.713262264354627 5.1877801804871915 1.1130427360157376 0.3580104692277669 0.000279780791542 0.1306031110532128 0.038473640150977 0.0046371283427721 0.000589307810219 Prostate gland development 2 5 2.444268401203152 0.0145146238446087 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.0753728904990679 0.1389130578490434 0.2613412907301976 0.1735315682069146 0.1889957663081205 Regulation of glial cell proliferation 1 5 2.433791695002331 0.014941591006957 0.9563106796116504 4.089805825242719 0.9341050469143442 0.3274204875894432 0.8829748814899869 0.9675276073756384 1.0425311720733597 0.2839327622585455 0.1011476887422587 1.0 0.152955667850895 0.0630532374058985 0.1985866733922443 Regulation of superoxide metabolic process 0 5 2.428140298851442 0.0151764711235209 1.087378640776699 4.303398058252427 0.5333775110261655 0.4533788529014697 1.287405731238345 0.6252674043851325 1.000392063299569 0.3127802017025773 0.405669230407056 0.0742352733278267 0.144637307685789 0.3258327648280404 0.5492603500015365 Lipid biosynthetic process 33 131 2.4266233153855894 0.0152400700745989 38.012135922330096 141.7257281553398 0.5620793375816577 0.4367444072022249 15.729119254593195 17.314902336322657 1.553306672697969 0.3832082090559359 7.047691017625031e-07 0.876472321166887 0.1188000617751801 0.0002724275713108 9.042883434338122e-05 Porphyrin containing compound metabolic process 5 18 2.424186654975266 0.0153427173787583 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.000755986230344 0.0121686135974036 0.045127039841821 0.0001749771036996 0.0062013164624522 Glycolipid catabolic process 3 7 2.423958843118532 0.0153523452717936 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 0.0004143495648334 1.0 1.0 0.0026581093268102 0.0019884945269669 Metal ion homeostasis 28 81 2.4187451564015188 0.01557414700951 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.0794274065099776 0.0083061448737759 0.112493321738286 0.0564867987008294 0.0311679518521572 Metal ion transport 36 103 2.4079676732387445 0.0160416013830992 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.1479900372781221 0.0251193707960862 0.0522811411854086 0.1419114141946443 0.0818329585001369 Protein hydroxylation 6 14 2.3986400801185868 0.0164560808710687 5.04126213592233 14.87621359223301 0.7765678108992397 0.4273021352291809 2.482119818897232 1.8660787070180411 0.9906439819977368 0.3285418073460514 0.0398919215908436 1.0 1.0 0.0197332243190265 0.0008083265510004 Signal peptide processing 3 5 2.389266636431638 0.0168820451355171 2.0898058252427183 5.155339805825243 0.788498872885968 0.2357910477072221 1.2938213743418876 0.7208043181852656 1.3841109341751536 0.2490116896927748 0.0044142958650036 1.0 0.1018169846714528 0.0020298329670106 0.0013781701696679 Protein transmembrane import into intracellular organelle 6 13 2.386385930926263 0.0170148848972442 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0023908367762777 0.0003865639533612 0.0029806631250197 0.0356014336373073 0.0004675519327548 Glial cell proliferation 2 6 2.365652991776629 0.0179983051846546 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.0357267845630647 1.0 0.2012104780589677 0.0175758241055335 0.0981468657129251 Energy derivation by oxidation of organic compounds 17 117 2.347999157701212 0.0188745639875831 30.652912621359224 122.18932038834951 0.2541815110246533 0.5071130371174295 12.61138398748304 8.311769788309597 1.4201467433346076 0.3884313364311733 0.0007962222708302 0.0288713637898469 0.0307457901430655 0.0002879543392999 0.0016589718556063 Regulation of hormone metabolic process 2 5 2.347527293832632 0.0188984884899412 1.9199029126213591 5.327669902912621 0.9387613573830266 0.3058102715557096 1.1578738425382251 0.5676654694542113 0.9983912186719198 0.2773016546183636 0.132890879981864 0.0919337377678228 0.1774332758731671 0.0840389641709933 0.2531867173469597 Protein import into mitochondrial matrix 2 8 2.345826960775769 0.0189849190957536 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0110723766410014 4.557535944516599e-05 0.0003712110430798 0.005208827916976 0.0048822579474643 Glycosaminoglycan catabolic process 3 5 2.3364642920030585 0.0194670565489472 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 0.0044142958650036 1.0 0.1018169846714528 0.0280420066437826 0.0140126286640228 Aminoglycan catabolic process 3 5 2.3364642920030585 0.0194670565489472 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 0.005747611298441 1.0 0.1105474823156849 0.0331187861076589 0.018020673376298 Intracellular protein transport 100 325 2.3351450435561807 0.0195358449225611 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 0.000606667174259 0.0003254373142102 0.0008741590567729 0.0005924314607118 0.0001413495018648 Protein processing 13 40 2.311813276377998 0.0207879754692781 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 0.0136277726402008 0.4904368630106878 0.1526361156980193 0.0020669790309363 0.0075219453181124 Vitamin transmembrane transport 4 6 2.308136219145515 0.0209915612552247 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0813807147607684 1.0 0.1362380906066266 0.050241067872642 0.0005289198821125 Diol biosynthetic process 3 8 2.300791112689325 0.0214034410413845 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0005835015228144 0.0017062060788896 0.0067896670197663 0.0002054625318554 0.0027630263410089 Diol metabolic process 3 8 2.300791112689325 0.0214034410413845 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0013765798902016 0.0026008925831016 0.0102498345034834 0.000493734331549 0.0062633876942655 Amyloid precursor protein biosynthetic process 2 5 2.2975838741553383 0.021585484327679 1.529126213592233 4.050970873786408 0.5724883308647799 0.4003128139433519 1.0007891127244537 1.1319816926742772 1.117383900072293 0.3129811194531851 0.0316229463164198 1.0 1.0 0.1988473022417859 0.0076703518288617 Proton transporting two sector atpase complex assembly 3 5 2.290282172630685 0.0220049645768902 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.0720062696786667 0.0652597674910206 0.1277572387780678 0.0442367692127036 0.0277461310389573 Nucleotide transmembrane transport 6 9 2.280083227806581 0.0226027527733203 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.405669230407056 1.0 1.0 0.3258327648280404 6.703246650942136e-05 Tetrapyrrole metabolic process 5 21 2.2752824695985208 0.0228889903729159 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0025833985940323 0.0188245552589776 0.0678620701894922 0.000633861319384 0.0187017730028202 Lipid localization 29 72 2.2747592583671903 0.0229203754960696 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 7.849923824874955e-06 0.6591545990918732 0.0204567166081377 2.704056667006821e-05 0.000179901890604 Protein insertion into mitochondrial inner membrane 4 7 2.264583372070183 0.0235382582561556 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 0.0004143495648334 0.0014481500629001 0.0001833288791406 0.0026581093268102 0.0001575214550341 Modified amino acid transport 3 5 2.264410282912644 0.0235488921085547 2.029126213592233 5.587378640776699 1.6181581718562612 0.1578136127091599 1.2124460606928238 1.444653995706506 0.7704353439327314 0.2037484924456972 1.0 1.0 1.0 1.0 0.2531867173469597 Purine containing compound transmembrane transport 6 10 2.261161485981013 0.023749259073855 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.365700423008737 1.0 1.0 0.2917500038862815 2.7323384312904545e-05 Mitochondrial calcium ion homeostasis 9 11 2.259127011840676 0.0238754853324472 4.62621359223301 10.509708737864075 0.2790428491871666 0.3774917598770124 2.1634860921400008 1.7383182679254283 1.294226020505384 0.3175561312397286 0.1439202931032497 0.0963063052639835 0.1854358412925483 0.0914454637274335 0.0003689915939861 Peroxisome organization 5 10 2.253809464168274 0.0242081571681489 4.286407766990291 11.196601941747574 0.606295801393023 0.4614466229190617 2.3307796330420754 2.613015983661412 0.9820420209440194 0.3193147518558685 0.2608845286829571 1.0 1.0 1.0 0.0033138804057902 Mitochondrial calcium ion transmembrane transport 5 11 2.246822272784033 0.0246513877386651 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.0133098681989492 0.0026008925831016 0.0102498345034834 0.0062969264366488 0.0007388687073799 Plasma lipoprotein particle clearance 5 11 2.2387172400533517 0.0251743200649177 2.8033980582524274 11.597087378640778 0.2841472336869506 0.2922439265613805 1.7215617505529983 1.5431625772865891 1.3638326625090953 0.2354738993646769 0.0246656034060207 0.0919337377678228 0.0158256043387446 0.0840389641709933 0.0002747300414667 Low density lipoprotein particle clearance 5 10 2.225270159920035 0.0260631073919008 2.628640776699029 10.633495145631068 0.2652848599989675 0.2775304047094778 1.52978680445189 1.394909057645927 1.3932465899654711 0.2286950604253255 0.0133098681989492 0.0742352733278267 0.0102498345034834 0.0565188023636715 6.703246650942136e-05 Protein depalmitoylation 2 5 2.221365648469116 0.0263262057234177 1.3203883495145632 4.468446601941747 0.9114659728007516 0.274733419943775 1.0188856680336909 0.6320520706114182 1.1467191069327447 0.2583665413440971 0.0387067647766449 0.0470522829573702 0.0039921150854813 0.0233125205204954 0.0105668672564949 Lipoprotein catabolic process 2 5 2.221365648469116 0.0263262057234177 1.529126213592233 5.211165048543689 0.7074087979902727 0.279320898549559 1.1111204061152251 0.9407555329409328 1.2623530327786678 0.2599848817817885 0.0813807147607684 0.0697581245313758 0.0090253131212995 0.050241067872642 0.0334620993119388 Endoplasmic reticulum tubular network organization 6 10 2.216012099803534 0.0266906734819247 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 0.0017552097648196 0.0786913117950012 0.152955667850895 0.0630532374058985 7.746328029618005e-06 Glycoprotein biosynthetic process 18 48 2.212951401843804 0.0269009963294102 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.5706370974001206 1.0 1.0 0.8455590741262777 0.0433448196180351 L amino acid transport 9 12 2.2101051572038557 0.0270978650333952 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.2967692865845885 1.0 1.0 0.5676800659750835 0.227264848110046 Positive regulation of mitophagy 3 5 2.208935112611563 0.0271791544958983 1.550970873786408 3.8689320388349513 0.8801808224672079 0.2696501569411311 1.2345448550586016 0.6553038465502932 1.2765039068030126 0.275295393283453 0.0140384652628863 0.028497516818446 0.0013648737359616 0.0082857576662697 0.0020376306093415 Regulation of blood pressure 10 18 2.208810067103558 0.0271878545333101 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0102086638570476 0.0315268496209905 0.0023751027082345 0.0131393408571549 0.0215069931551279 Amyloid precursor protein catabolic process 6 17 2.207537642821601 0.027276520157718 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0511591174541085 0.0188245552589776 0.0678620701894922 0.0216647555097342 0.0048940429574069 Phosphatidic acid metabolic process 2 6 2.2053404599410946 0.0274302126944023 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.048921629591182 1.0 0.2243071172363204 0.0244664942800011 0.1298078118605267 Endoplasmic reticulum membrane organization 5 7 2.200628049344187 0.0277623662103885 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.0072968442312668 1.0 1.0 0.0385233102424958 0.0002457979454447 Macromolecule depalmitoylation 2 6 2.1940377696294697 0.0282326943824879 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.005747611298441 0.0014481500629001 0.0001833288791406 0.0026581093268102 0.0019884945269669 Regulation of steroid metabolic process 4 14 2.190261579454271 0.0285052715345324 4.334951456310679 14.769417475728156 0.4748357054552781 0.3599056508632772 2.2294240946396933 1.955260926764874 1.2378399088740557 0.2930403635554361 0.0246839298564812 0.2220822570468345 0.3986935444378103 0.1323508586296182 0.106558868417216 Glycoside catabolic process 3 6 2.189338013018827 0.0285722814060251 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 6.487532278076852e-05 1.0 0.075113296023457 2.214766218704514e-05 0.0003286021100258 Regulation of membrane lipid distribution 4 9 2.1890503561325825 0.0285931802004488 2.2475728155339807 5.5 0.9490281853542848 0.2470521989607894 1.5110816970578842 2.070950253254846 1.235309366119274 0.2447223644308076 0.010067670651814 1.0 0.0021930786590517 0.0038594647505617 0.008785557350241 Protein mannosylation 2 5 2.188972023446564 0.0285988734923119 1.230582524271845 3.5776699029126213 0.5262069874103198 0.4175627359044286 0.9667966576123064 0.8397216412152502 1.108389625854248 0.3033484504285141 0.4247018267592247 1.0 1.0 1.0 0.0465653262864464 Calcium import into the mitochondrion 5 8 2.169658080306192 0.0300327579305663 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 0.005747611298441 0.0014481500629001 0.0057815105752346 0.0026581093268102 0.0001575214550341 Regulation of cholesterol metabolic process 2 6 2.168568958184723 0.0301154240103731 2.2936893203883497 7.036407766990291 0.4249970400619817 0.3648416816190511 1.505220359503101 1.431658251221006 1.1754439785533268 0.2764552996129673 0.0398919215908436 1.0 1.0 0.4465871194719102 0.1083207684216986 Steroid biosynthetic process 15 43 2.167647859421552 0.0301854894044628 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.000257606199461 0.3746890061856052 0.0681445056645133 0.0092901014583675 0.0007877209523169 Sterol biosynthetic process 7 22 2.1634878188085804 0.0305036796279321 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 0.0001060645878057 1.0 0.0761270368947914 0.00545325875553 0.0003639341338094 Protein localization to organelle 103 320 2.1618501900746443 0.0306297253894198 67.3495145631068 323.95873786407765 0.2673038377247629 0.817015428896562 19.766210620364816 30.728939371736654 0.7017218037327799 0.31039729979455 0.0011078504961895 0.0223887443305945 0.0245915261697326 0.0033718328622016 1.9719525589848935e-05 Cellular homeostasis 39 142 2.157966143544205 0.0309304641900594 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.1323403219270915 0.0513484222325217 0.392578268883714 0.0291372306083628 0.0878016114871136 Cellular macromolecule localization 156 542 2.155336249142487 0.0311355311338954 116.74029126213593 544.3228155339806 0.3819130491508938 0.7577794226812853 28.882302639166586 53.383983306101904 0.8794377571334007 0.3523979567946485 0.0024959091427145 0.0443997614908677 0.0475479169819333 0.0064875977438681 5.253196769472084e-05 Transition metal ion transport 4 13 2.1533835307982634 0.0312885488431735 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0397711326757236 1.0 0.4386006499544391 0.0549638769430376 0.1573271124776855 Regulation of ire1 mediated unfolded protein response 3 5 2.133494687938823 0.0328841669567421 2.1771844660194173 5.672330097087379 0.5038262411650992 0.5038506797739859 1.3293416996099243 0.6512955034264291 0.8607100577092882 0.3177321851812736 0.0387067647766449 1.0 1.0 0.2183511668733661 0.0817606313480972 Protein insertion into er membrane 6 13 2.1303499752268684 0.0331427305084088 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 0.0317991274542054 1.0 0.1933613304033528 0.0990342687178565 0.0200033311952484 Ph reduction 3 12 2.1255078143132686 0.0335442627260236 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0114560625613426 0.0078974776787256 0.0299460957191466 0.0044180066438726 0.0446088038944012 Transition metal ion homeostasis 6 26 2.118840675433693 0.0341039339251834 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0138399534336496 0.0066118310835921 0.0426450873703444 0.0130864958075334 0.0929128113500605 Connective tissue development 7 23 2.1141658472713893 0.034501104748061 6.759708737864078 24.91747572815534 0.897701915164713 0.400129048313066 2.7453452066208146 3.8608044632925673 0.8993390896039578 0.3237981500894625 0.1158154049314376 0.462328834210194 0.3537506045033747 0.2012009363655057 0.2823885123147982 Respiratory chain complex iv assembly 4 7 2.1079212452152167 0.0350378022018191 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.0076288979420162 0.1135912525516411 0.2166826538338764 0.0028897230126965 0.0062616815035888 Atp metabolic process 15 103 2.106804636790897 0.0351345174157211 25.97087378640777 107.69417475728156 0.2650120939459569 0.5409439866831242 10.270805368899644 8.059768543771504 1.2580915670575048 0.3757529915372982 0.0012027681961772 0.0182713904115901 0.0166742060342669 0.0006365205059399 0.0031973336967402 Divalent inorganic cation homeostasis 19 55 2.104981905085579 0.0352928832051655 15.361650485436892 54.019417475728154 0.5485088157809707 0.5170537035394376 6.04857242197355 6.215359275440269 1.1779017300469032 0.3778837346959196 0.1323983082817975 0.2194767361872623 0.5334858344414195 0.1585171559804351 0.0327388143271522 Mitochondrial electron transport cytochrome c to oxygen 3 6 2.101389683458874 0.0356067728181181 2.6189320388349513 6.021844660194175 0.7576771538928655 0.3133819177040797 1.4641113893518565 0.9306060741204804 1.2097595052740109 0.2966582872605096 0.005747611298441 1.0 1.0 0.0026581093268102 0.0019884945269669 Peptidyl proline hydroxylation to 4 hydroxy l proline 2 5 2.097914923223418 0.0359126614915039 1.91747572815534 4.978155339805825 0.4438057662566078 0.4820538119388955 1.3267177679592008 0.5324503670252024 0.940328511916904 0.3132987011445886 0.2035074389511066 1.0 1.0 0.1583736196074974 0.0034377129995212 Response to food 2 5 2.093084720104036 0.036341592459445 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 0.0630153283272142 0.0607401038440192 0.1191939669275513 0.0385233102424958 0.0225979674873623 Lipoprotein localization 2 7 2.085645414859781 0.037010754308459 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.005747611298441 1.0 0.1105474823156849 0.0026581093268102 0.018020673376298 Glial cell migration 3 12 2.0853032628988903 0.0370417814397017 3.1480582524271843 11.75485436893204 0.4903114278901663 0.4024923853285767 1.6265160564973062 1.1535511772771148 1.0147729417330946 0.2731057446682498 0.010067670651814 1.0 0.2318581098993339 0.0038594647505617 0.008785557350241 Positive regulation of mitochondrion organization 11 22 2.0748615912131365 0.0379993643236942 6.235436893203883 22.393203883495147 0.6669540243221574 0.4355223453199826 2.7589935116766484 2.962672702300372 1.01251720769805 0.3295170825531805 0.0886794531572386 0.225839943305071 0.0146485330026984 0.0395157416890983 0.0423415641222214 Protein catabolic process in the vacuole 2 6 2.0728572980087487 0.0381855621075739 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0246656034060207 0.0919337377678228 0.0158256043387446 0.0119341177484456 0.0143001062154138 Lysosomal protein catabolic process 2 6 2.0728572980087487 0.0381855621075739 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.0185029536171668 0.083126337411673 0.012905013470629 0.0088528623379573 0.0097510399506001 Glycosyl compound catabolic process 6 10 2.063081330107004 0.039104901674815 3.216019417475728 9.74271844660194 -0.2866012386822237 0.2471021044870933 1.8641835401772064 0.9067280280460008 1.4904201092322935 0.2120144867281597 0.0008343534134802 1.0 0.208984012191681 0.0002379581347217 0.0008083265510004 Amino acid transport 14 21 2.061560072061841 0.0392496387116347 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.3799812878539559 1.0 1.0 0.8181940718302647 0.0492141807689911 I kappab kinase nf kappab signaling 6 43 2.0586875669391183 0.0395241780280639 10.145631067961164 49.810679611650485 0.360044073400616 0.6099848557681691 4.404119358078279 7.130073225312779 0.7921548119294252 0.3279566448560211 0.379640013137515 0.0589716158536245 0.2675814658558231 0.2951305433925472 0.8007813647913742 Protein localization to endoplasmic reticulum 15 32 2.053849738060584 0.0399902372585649 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0349998460451032 1.0 0.4274740864709498 0.0494987487524972 0.0003655904724143 Positive regulation of protein exit from endoplasmic reticulum 2 5 2.0474922513033755 0.0406097769042343 1.7014563106796117 3.842233009708738 0.6319527754438191 0.4528969328253339 1.0729226103046268 0.876811779781035 1.0096007730201175 0.3294914749708005 1.0 1.0 1.0 1.0 0.3285208438252537 Cellular monovalent inorganic cation homeostasis 8 25 2.044744720095041 0.0408800322577802 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.1304258290921289 0.0345877004093447 0.1182995834221419 0.0607417341965242 0.0744808849197366 Lipid translocation 5 8 2.0432454430084825 0.0410281473063407 1.720873786407767 4.390776699029126 0.721199302569061 0.3015554657161993 1.2968412758505727 1.7626690867431634 1.2167340583298332 0.2614747358309583 0.0317991274542054 1.0 0.0190005699483642 0.0155574138143109 0.0200033311952484 Regulation of lipid metabolic process 13 49 2.033365547252184 0.0420156054126716 12.599514563106796 52.890776699029125 0.2189053156740071 0.4007176079141414 5.562295027948738 7.005213895866115 1.3822804240908182 0.3523493088444139 0.0032679343129689 0.0636643545059936 0.0106167329930639 0.0069656807398177 0.0812271147966727 Positive regulation of mitochondrial calcium ion concentration 4 5 2.032901999723088 0.0420624249756813 2.228155339805826 5.211165048543689 0.1418363032358024 0.4109308835680456 1.2312214690975103 1.149745265979588 1.1823006355769805 0.3144055905104015 1.0 1.0 1.0 1.0 0.0105668672564949 Copper ion homeostasis 2 5 2.0244299520444 0.0429259325410502 1.6771844660194175 4.669902912621359 0.4484316971142749 0.3058603694529516 1.2128614304476144 1.4202990900289796 1.3716690980071935 0.284002300922153 0.0911051214117314 1.0 1.0 0.3258327648280404 0.1807018090276839 Protein insertion into er membrane by stop transfer membrane anchor sequence 1 5 2.0234204708840897 0.043029815401572 1.9635922330097089 5.686893203883495 0.4346685280287892 0.4212908647152366 1.4128861560779629 1.136987613501037 1.0888942312003185 0.31377177158709 0.27754648329827 1.0 1.0 1.0 0.0817606313480972 Negative regulation of regulated secretory pathway 0 5 2.015326675720762 0.0438704316501854 0.9781553398058253 4.398058252427185 0.7700890595439712 0.3703070501759239 1.164611062683957 0.8514956096808038 0.9880129676694246 0.2942343620509365 0.3230525045126784 0.0561990347849709 0.1105474823156849 0.2559514735144251 0.4498304155532511 Regulation of lipase activity 5 11 2.0071291699586813 0.044735910992248 3.262135922330097 11.20873786407767 0.5080857493577803 0.3640362286084045 2.107366483573331 1.390020380944142 1.1722840995258883 0.3007278087276755 0.0379890255395893 0.1755724648168266 0.3236452024265956 0.072741111398958 0.1274755097437061 Mitochondrial atp synthesis coupled proton transport 2 11 2.000551781109704 0.0454407143728934 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.0185029536171668 0.083126337411673 0.012905013470629 0.0088528623379573 0.0097510399506001 Glycolipid biosynthetic process 5 8 1.9983431992461267 0.0456794650992045 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.1068109103028516 1.0 1.0 0.5885248237912099 0.2535314416198171 Protein import 27 88 1.996438933530348 0.045886166516871 18.941747572815533 84.88106796116504 0.6008949453203009 0.582747226306641 7.950789473798742 5.928615059974957 0.9194508312715092 0.3730411656244653 0.0577285280525975 0.0015312980941649 0.0288090143646809 0.140523532509772 0.0252758805219831 Apoptotic mitochondrial changes 8 32 1.9876342539816856 0.0468521550517588 8.33495145631068 31.9126213592233 0.3104951463965997 0.5709370276570955 3.5539451273925566 2.6332703138780773 0.8593316992754738 0.3196919958634499 0.0876483839252153 0.3007677906227077 0.0350615001471499 0.0338869207736729 0.0092851689807755 Gpi anchor metabolic process 2 5 1.9837009661614595 0.0472891858049786 2.400485436893204 5.657766990291262 0.3080589762515228 0.4676033624934861 1.4738167072879584 1.5318187882629617 1.0335174561584772 0.3098879122060578 1.0 1.0 1.0 1.0 1.0 Peptidyl lysine hydroxylation 1 6 1.9820806818509928 0.0474702112988052 1.9077669902912624 6.308252427184466 0.5185432142936987 0.5039052199507211 1.4816803187819223 1.2712771097123454 0.8587843232642178 0.3110172359904222 0.0316229463164198 1.0 1.0 0.0189506401306209 0.0675218785318175 Regulation of steroid biosynthetic process 4 10 1.9805944970160252 0.0476367665672137 3.186893203883495 10.259708737864075 0.6168896095149775 0.3174156062343823 1.783561142158544 1.373475469974866 1.265753415239616 0.2847701277650337 0.0068384593966298 0.1675604235637086 0.3102657432506607 0.064307133891248 0.0353817250131281 Autophagy of mitochondrion 10 31 1.979049237049004 0.0478104629874027 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 0.0956198421586395 0.3075216202298709 0.1682749782688163 0.0373973333253586 0.0304896229948475 Pigment metabolic process 5 27 1.978124790571826 0.0479146305332789 6.730582524271845 27.429611650485437 0.7330558837492486 0.3938325994367372 3.1680652652278396 2.973572406869117 1.1788232115476622 0.3357800616079686 0.0079165355623873 0.0285808600856777 0.0995728547031488 0.0020840105698312 0.0164244734054917 Hormone metabolic process 10 30 1.97359887240147 0.0484273720660741 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.035542426887442 0.078986772223975 0.0681445056645133 0.0092901014583675 0.0190063352955717 Pinocytosis 0 7 1.9734239098871484 0.0484472857432847 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 0.4431267412364788 0.083126337411673 0.1611939416425752 0.3582816735878424 0.5920308942141137 Peptide catabolic process 4 10 1.9719550268912744 0.0486147407271551 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.002717792968079 1.0 0.0143328298354406 0.0103266247469619 0.0017429018144962 Peptidyl proline hydroxylation 4 7 1.9677848446089776 0.0490927986866029 2.9393203883495147 7.366504854368932 0.8317722887875127 0.3653030215718857 1.5036226559632782 0.8268224457358132 1.022007383809078 0.3112189596123257 0.3230525045126784 1.0 1.0 0.2559514735144251 0.0019884945269669 Positive regulation of i kappab kinase nf kappab signaling 3 31 1.9648313161128743 0.0494337643542073 7.344660194174757 35.86407766990291 0.4790737148931881 0.5397451864543208 3.344702467076835 5.27321228840899 0.8885741992578381 0.3336801499419705 0.3704379774983926 0.0220060448297376 0.1215759638014328 0.3619411972926146 0.7323993351764969 Regulation of toll like receptor signaling pathway 2 9 1.964526255645353 0.0494690945252882 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.3904638548151614 1.0 1.0 0.2722557910873528 0.3340933889960909